Sample Management Manager

About the role

Join Natera’s R&D operations as the Sample Management Manager. You will direct biobanking, cold chain logistics, and the full lifecycle of clinical diagnostic samples. Every sample represents a real person, and you will ensure that tracking, storage, and distribution meet the rigorous standards required to advance cell-free DNA testing.

Primary Responsibilities

• Develop and implement standardized procedures for sample intake, storage, tracking, and distribution

• Treat regulatory guidelines (e.g., GMP, GLP, ISO) and company policies as the foundation of your work, ensuring strict compliance

• Manage Laboratory Information Management Systems (LIMS) to maintain sample integrity and traceability

• Lead, train, and develop the Sample Management team to operate with pace and precision

• Think team by partnering directly with R&D, Quality, Supply Chain, and external partners to align sample management practices without needing translation layers

• Use data to troubleshoot discrepancies, root-cause logistical issues, and resolve quality concerns

• Use data to pressure-test workflows and implement technology enhancements that improve precision and scale

• Prepare rigorous reports and audits to support quality assurance and regulatory inspections

Operational Responsibilities

• Take ownership of sample management operations, proactively allocating resources and designing workflows to meet rigorous clinical timelines

• Provide clear guidance to the team, establishing policies and removing operational bottlenecks without relying on heavy hierarchy

• Manage scheduling, performance requirements, and operational budgets

• Act as an advisor to the team, directly stepping in to assist with issue resolution and technical troubleshooting

Team & Performance Management

• Direct team members to ensure precise execution of SOPs and safety procedures

• Oversee training for new hires and build an execution-focused culture

• Conduct regular 1:1 meetings to deliver unvarnished, data-backed performance evaluations and discuss goals

• Plan and lead shift meetings, fostering team alignment and professionalism

• Approve timecards, PTO requests, and ensure consistent staffing coverage

• Prioritize workloads dynamically, delegate responsibilities, and escalate issues without hesitation

Compliance & Quality Assurance

• Treat quality as part of performance by ensuring all regulatory agency requirements are met through proper documentation, audits, and corrective actions

• Maintain strict compliance with HIPAA/PHI privacy policies and complete required training within 30 days of hire

• Oversee sample processing, ensuring accurate documentation and adherence to departmental expectations

• Support R&D leadership in initiating and executing new projects to enhance operational efficiency

Qualifications

• BS/BA degree (Master’s degree preferred) in Medical Technology, Biological Sciences, or a related field

• 8+ years of related experience with a bachelor’s degree

• Minimum 3 years of team management experience

• Demonstrated team management experience in a fast-paced, regulated environment

• Ability to manage projects independently with an ownership mindset

• Clear, direct communication and troubleshooting skills

• Excellent pipetting, data analysis, and wet lab operations abilities

• Proficiency in Laboratory Information Management Systems (LIMS) and data analysis tools

• Experience with Molecular Biology, Good Manufacturing Practice (GMP), and Quality System Regulation (QSR)

• Strong Excel and data management software experience

• Experience with biorepository sample management is a plus

• Strong knowledge of regulatory requirements in sample handling is preferred