Postdoctoral Fellow-MSH-32074-065

Salary: $74,692

Department: Cardiovascular Research Institute

Physical work location: 1470 Madison Ave, Hess Bldg, 7th Fl, New York, NY 10029

Principal Investigator: Cameron McAlpine, 857-207-8093, Cameron.mcalpine@mssm.edu

Lab website | Department website

Administrative Contact: Mikaela Walcott, Mikaela.walcott@mssm.edu, 212-824-8907

About the role

Title: Evaluate neuronal control of macrophage function in the heart. The candidate will use fundamental science tools to test how the nervous system regulates macrophage function and biology in the heart. The candidate will test how neurotransmitters and neuropeptides modify macrophage subsets and inflammatory processes in the heart and its vasculature at steady state, after myocardial infarction, during atherosclerosis, or in the context of other cardiovascular pathologies.

Responsibilities

• Mouse modeling and handling
• Flow cytometry
• Advanced confocal imaging of the heart
• Single-cell sequencing
• Neuronal manipulation methods (neuronal ablation, neuropeptide deletion, brain circuit manipulation)
• Molecular assays (protein quantification, mRNA expression)

Goals

We will identify new ways by which the nervous system regulates inflammation in the cardiovascular system. Novel signaling mechanisms will be further developed and tested for therapeutic intervention.

Requirements

• PhD
• 0 years of experience required

About the employer

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare.

We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. Our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization.

About The Mount Sinai Health System

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it.

The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked in multiple specialties.

Pay

The salary range for the role is $72,500 - $80,000 annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The range does not include bonuses, incentive pay, differential pay, or other forms of compensation or benefits.