Sr. Associate Scientist, R&D Chemistry, Peptidomimetic Purification

About the role

We are currently seeking a lab-centric peptide purification chemist to join the R&D (Research & Development) Chemistry group. In this position, they will play a key role in Regeneron’s peptidomimetic antibody-conjugate drug discovery capabilities to enable seamless combination with the company’s existing expertise in biologics and novel genetic medicines.

Responsibilities

• Drive the purification of peptidomimetic payloads and linker payloads for antibody conjugate drug therapeutics across diverse research areas.
• Troubleshoot and optimize peptide purification methods and enable high throughput purification and isolation.
• Identify new strategies and technologies for peptidomimetic purification to improve on existing Regeneron techniques.
• Actively participate in departmental, cross-functional, leadership, and external meetings to contribute expertise and to represent the vision of the R&D Chemistry Peptidomimetic purification team.
• Interact broadly and collaboratively with other Regeneron groups, forging relationships and active collaborations.

Requirements

• Bachelor’s degree required, Master’s degree preferred in peptide, peptidomimetic, small molecule purification.
• Minimum of 5 years of industry experience.
• Extensive hands-on experience of the HPLC purification/detection and method troubleshooting of peptidomimetics.
• Hands-on experience with Waters and/or Agilent purifications systems preferred.
• Hands-on experience with mass-triggered collection preferred.
• Extensive experience running modern purification/isolation equipment and instrumentation.
• A track record of success in the field of either peptidomimetics or small molecules purification is required.
• Experience working collaboratively with both internal and external organizations (e.g., CROs) is essential.

Qualifications

• Passion and enthusiasm about the promise of peptidomimetic conjugated, antibody-targeted therapeutics and how peptide purification can enable their generation.
• Enjoy applying and combining traditional methods and novel technologies to develop solutions for purification.
• Comfortable working in a cross-functional role and excel in a diverse team where egos are checked at the door.
• Willingness to provide meaningful contributions to the development of an organizational culture that supports growth and development of its people and capabilities to drive forward the Regeneron pipeline.
• Desire to work in an organization that is modality agnostic, letting the data determine the best course forward.

Skills

• Strong communication and collaboration skills.
• Ability to troubleshoot and optimize purification methods.
• Knowledge of modern purification instrumentation and techniques.

Benefits

• Annual bonuses or other incentive plans.
• Equity awards.
• Pension or retirement benefits.
• 401(k) company match.
• Health and wellness programs.
• Fitness centers.
• Insurance benefits (e.g. medical, dental, vision, life and disability).
• Paid time off.
• Family support benefits.

Pay

$80,300.00 - $131,100.00 annually

Schedule

Full-time