Senior Scientist l, QTAS & ADME Sciences

About the role

The Senior Scientist, Quantitative, Translation & ADME Sciences (QTAS) will play a pivotal role in advancing AbbVie's translational ADME strategy through innovative and quantitative approaches. The ideal candidate will have a strong background in in vitro models, drug metabolizing enzyme function, drug-drug interaction concepts, quantitative bioanalysis, and experience in adjacent areas like drug permeability and transport, receptor pharmacology, and pharmacokinetic modeling.

Responsibilities

• Laboratory experimentation in cellular and subcellular models
• Evaluating novel in vitro tools and methods, and applying established methods and concepts to enable and improve prediction of human PK and drug-drug interaction potential
• As needed, liaising with QTAS, discovery biology/pharmacology to generate data and knowledge supporting the build-up of translational, mechanistic models
• Communicating internally and externally on topics related to in vitro drug metabolism
• Keeping up to date with emerging literature and science in modeling and in vitro approaches

Qualifications

• Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary
• Strong experience in cell culture methods, including hepatocytes and cell lines
• Deep understanding of drug metabolism and ADME principles including enzyme kinetics, IVIVE and DDI risk assessment
• Strong and relevant publication record
• Highly motivated, self-driven and results-oriented person with excellent communication and presentation skills, capable to work both as team player and independent scientific contributor
• Passion for generating ideas, learning, solving technical problems and applying new technologies to further scientific goals

Key Leadership Competencies

• Buils strong relationships with peers and cross-functionally with partners outside of team to enable higher performance
• Ability to inspire and lead others in areas of your expertise
• Learns fast, grasps the "essence" and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation and manages innovation to reality

Benefits

• Comprehensive benefits package including paid time off, medical/dental/vision insurance, and 401(k)
• Short-term incentive programs

Pay

$96,500 - $183,500 USD