Senior Scientist I, Quantitative, Translational, and ADME Sciences (QTAS)

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube. Job Description The Biomarker team of Quantitative Translational ADME Science (QTAS) at AbbVie in Worcester, MA is seeking an experienced, creative, and highly motivated senior scientist to support bioanalytical method development, validation and preclinical/clinical sample testing for the discovery and development of novel therapies in multiple therapeutic areas. The Biomarker team focuses on PCR-based assays as well as ligand binding assays (LBA) to support exploratory and translational research that enables decision-making. The ideal candidate should have hands-on experience in a variety of technologies, including but not limited to qPCR, dPCR, ligand binding assays, high sensitivity and multiplex assays, sample processing and handling, etc. The candidate will be a key member of a global non-regulated bioanalysis team that support all AbbVie therapeutic areas. Responsibilities Develop, qualify, and validate robust bioanalytical qPCR and dPCR workflows on a variety of sample matrices from a variety of species.Experienced with various ligand binding assays on multiple analytical platforms across a variety of sample matrices.Conduct and document appropriately compliant biomarker sample testing to support pre-clinical and clinical studies.Plan and executein vivo sample analysis based on bioanalytical protocol and study design.Interpret, present, and discuss assay results; use results to guide analysis and adjust strategy. Communicate experimental plans and results effectively, both verbally and in writing during regular lab meetings and with broader teams.Develop effective partnerships with discovery, preclinical safety, clinical pharmacology, and project team representatives in a highly collaborative and innovative environment to deliver high-impact quality data in a timely manner.Evaluate novel, pipeline-enabling,bioanalytical technologies to expand capabilities and enhance efficiency.Maintain timely laboratory notebooks (ELN) and LIMS records in compliance with AbbVie policies.Strong organization and communication skills, proactive, attention to detail, critical thinking, troubleshooting skills, independence, multitasking, desire to learn new techniques, and contribute to cutting-edge projects. Qualifications Bachelors Degree or equivalent education with 10 or more years of relevant experience, Masters Degree or equivalent education with 8 or more years of relevant experience, or PhD (molecular biology, biochemistry, or other related fields, preferred).Extensive and proven experience in PCR-based bioanalytical workflows for pre-clinical and clinical projects, especially in DNA/RNA purification and qPCR, dPCR, etc.Proficiency with computers and data analysis/documentation software including platform specific tools, LIMS, and ELNWorking knowledge of LBA (ELISA, MSD, etc.) biomarker bioanalytical assay development, validation, and sample testing workflows to comply with current regulatory standards and best industry practices.Excellent communication skills, and proven ability to work effectively as a member of a multidisciplinary team.Demonstrated capacity to work in a fast-paced environment with meticulous attention to detail, and an ability to handle multiple projects, prioritize work, and meet deadlines.Working knowledge of handling clinical samples is a plus.Working knowledge of automation is a plus. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture.We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.This job is eligible toparticipate in our short-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html