Principal Research Scientist, QTAS & ADME Sciences

About the role

The Principal Research Scientist, Quantitative, Translation & ADME Sciences (QTAS) will play a pivotal role in advancing AbbVie's translational ADME strategy. This individual will be responsible for evaluating novel in vitro tools and methods, leading the development of predictive models, and collaborating with various teams to ensure rapid advancement of drug candidates.

Responsibilities

• Evaluating novel in vitro tools and methods, and apply established methods and concepts to enable and improve prediction of human PK and drug-drug interaction potential
• Lead, mentor, and coach junior staff in established and novel practices in vitro drug metabolism
• Liaise with QTAS, discovery biology/pharmacology/chemistry scientists to generate data and knowledge supporting the build-up of translational, mechanistic models
• Communicate internally and externally on topics related to in vitro drug metabolism
• Keep up to date with emerging literature and science in modeling and in vitro approaches
• Externalize research in the form of full-length publications and oral presentations

Requirements

• BS or equivalent education and extensive, typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; PhD with typically 6+ years of experience in area or scientific area of discipline
• Experience within vitro ADME experiments and DMPK projects, through academic or industry work
• Deep understanding of drug metabolism and ADME principles including enzyme kinetics, IVIVE and DDI risk assessment
• Strong and relevant publication record as well as a track record of strategic scientific leadership in the in vitro ADME field
• Highly motivated, self-driven and results-oriented person with excellent communication and presentation skills, capable to work both as a team player and independent scientific contributor
• Passion for generating ideas, learning, solving technical problems, and applying new technologies to further scientific goals

Qualifications

• BS or equivalent education and extensive, typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; PhD with typically 6+ years of experience in area or scientific area of discipline
• Experience within vitro ADME experiments and DMPK projects, through academic or industry work
• Deep understanding of drug metabolism and ADME principles including enzyme kinetics, IVIVE and DDI risk assessment
• Strong and relevant publication record as well as a track record of strategic scientific leadership in the in vitro ADME field
• Highly motivated, self-driven and results-oriented person with excellent communication and presentation skills, capable to work both as a team player and independent scientific contributor
• Passion for generating ideas, learning, solving technical problems, and applying new technologies to further scientific goals

Benefits

• Paid time off (vacation, holidays, sick)
• Medical/dental/vision insurance
• 401(k) plan

Pay

The salary range for this position is $124,500 - $236,500 USD. The actual salary offered will depend on various factors including geographic location.

Schedule

The start date for this position is June 8, 2026.