Senior Scientist l, QTAS & ADME Sciences

About the role

The Quantitative, Translation & ADME Sciences (QTAS) team at AbbVie seeks a highly motivated and experienced scientist to join their team in North Chicago. The ideal candidate will have a strong background and expertise with in vitro models, drug metabolizing enzyme function, drug-drug interaction concepts, quantitative bioanalysis, and ability to spot, ideate, and drive cutting-edge science.

Responsibilities

• Participate in implementing innovative and quantitative approaches to advance translational ADME using conventional as well as more complex in vitro models.
• Conduct and contribute to scientific leadership of in vitro assays.
• Apply translational modeling concepts to help drive the global in vitro ADME strategy at AbbVie.
• Qualify, confirm, and evaluate new technologies.
• Execute operational activities to support the mechanistic and translational understanding of early and late-stage small molecules to help advance drug candidates in the pipeline.
• Contribute to broader areas within DMPK as your experience and expertise warrant.

Qualifications

• Bachelor's Degree or equivalent education and typically 10 years of experience, or Masters Degree or equivalent education and typically 8 years of experience, or PhD and no experience necessary.
• Strong experience in cell culture methods, including hepatocytes and cell lines.
• Deep understanding of drug metabolism and ADME principles including enzyme kinetics, IVIVE, and DDI risk assessment.
• Highly motivated, self-driven, and results-oriented person with excellent communication and presentation skills, capable of working both as a team player and independent scientific contributor.
• Passion for generating ideas, learning, solving technical problems, and applying new technologies to further scientific goals.

Key Leadership Competencies

• Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance.
• Inspires and leads others in areas of expertise.
• Learns fast, grasps the "essence," and changes course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation, and manages innovation to reality.