Senior Scientist I, Quantitative, Translational, and ADME Sciences (QTAS)

Responsibilities

• Develop, qualify, and validate robust bioanalytical qPCR and dPCR workflows on a variety of sample matrices from a variety of species.
• Experienced with various ligand binding assays on multiple analytical platforms across a variety of sample matrices.
• Conduct and document appropriately compliant biomarker sample testing to support pre-clinical and clinical studies.
• Plan and execute in vivo sample analysis based on bioanalytical protocol and study design.
• Interpret, present, and discuss assay results; use results to guide analysis and adjust strategy.
• Communicate experimental plans and results effectively, both verbally and in writing during regular lab meetings and with broader teams.
• Develop effective partnerships with discovery, preclinical safety, clinical pharmacology, and project team representatives in a highly collaborative and innovative environment to deliver high-impact quality data in a timely manner.
• Evaluate novel, pipeline-enabling, bioanalytical technologies to expand capabilities and enhance efficiency.
• Maintain timely laboratory notebooks (ELN) and LIMS records in compliance with AbbVie policies.

Qualifications

• Bachelor’s Degree or equivalent education with 10 or more years of relevant experience, Master’s Degree or equivalent education with 8 or more years of relevant experience, or PhD (molecular biology, biochemistry, or other related fields, preferred).
• Extensive and proven experience in PCR-based bioanalytical workflows for pre-clinical and clinical projects, especially in DNA/RNA purification and qPCR, dPCR, etc.
• Proficiency with computers and data analysis/documentation software including platform specific tools, LIMS, and ELN
• Working knowledge of LBA (ELISA, MSD, etc.) biomarker bioanalytical assay development, validation, and sample testing workflows to comply with current regulatory standards and best industry practices.
• Excellent communication skills, and proven ability to work effectively as a member of a multidisciplinary team.
• Demonstrated capacity to work in a fast-paced environment with meticulous attention to detail, and an ability to handle multiple projects, prioritize work, and meet deadlines.
• Working knowledge of handling clinical samples is a plus.
• Working knowledge of automation is a plus.