Senior Scientist, Cell Therapy Research, Molecular Immunobiology and Discovery Team (In vivo CAR-T)
About the role
The Cell Therapy Molecular Immunobiology and Discovery team is seeking a highly motivated, dynamic and self-driven individual to help us build out our molecular engineering and gene delivery capabilities. Effective delivery of optimal cargo will be the foundation of our next generation of cell therapies. Innovations in this space will drive the future of our cellular therapeutic pipeline at BMS, enabling us to bring best-in-class engineered drugs to our patients. This role will primarily focus on developing and validating technologies to efficiently generate potent CAR-T cells. The ideal candidate is an experienced molecular biologist and lentivirologist with a strong background in immunology. They will have a conceptual and practical understanding of CAR-T cell biology, and knowledge of key challenges related to lentiviral vector transgene delivery in vitro and in vivo. This role will provide a challenging but rewarding opportunity for career development and is ideal for a scientist with an innovative mindset. Previous experience in cellular therapy, industry or academic, is preferred.
Responsibilities
- Plan and implement critical studies required for platform building and hypothesis-driven research for building the next generation lentiviral vectors
- Apply extensive knowledge of lentiviral vector biology to develop and execute creative strategies for increasing yield, throughput, and the robust streamlined assessment of novel lentiviral vector platforms