Senior Scientist, Cell Therapy Discovery

About the role

AstraZeneca is seeking a highly motivated and independent Senior Scientist with demonstrated experience and expertise in Cellular Therapy, Immunology, and/or Immuno-Oncology to join our rapidly growing Cell Therapy Team. The role will be based in Gaithersburg, MD.

Responsibilities

• Conducts hands-on drug discovery research experiments independently
• Affirms and reports data with a clear understanding of its implications within the overall context of drug discovery, independently formulate conclusions, and determine future experiments
• Works collaboratively in a matrix environment
• Shares relevant external published papers with peers
• Prepares and delivers presentations within the Cell Therapy Unit and across other functions
• Ensures own work, and work of peers, is compliant with relevant internal AstraZeneca standards and external regulations

Requirements

• Well-developed understanding and expertise in cellular and molecular biology of immune cells
• Expertise in genetic engineering platforms (CRISPR/Cas9), transfection/transduction, expansion, and cell culture of primary T cells and tumor cell lines
• Strong proficiency in multi-parameter flow cytometry (Immunostaining, acquisition, and analysis)
• Hands-on expertise in T-cell functional characterization assays such as in vitro cytotoxicity, proliferation, and cytokine measurement
• Molecular engineering and construct/plasmid design
• Experience with IO biologics (T-cell engagers, bispecific antibodies)
• Ability and motivation to drive projects to completion in a team environment

Qualifications

• PhD in immunology or relevant disciplines
• Minimum of 3 years of experience in Cellular Therapy, Immunology, and/or Immuno-Oncology

Skills

• Well-developed understanding and expertise in cellular and molecular biology of immune cells
• Expertise in genetic engineering platforms (CRISPR/Cas9), transfection/transduction, expansion, and cell culture of primary T cells and tumor cell lines
• Strong proficiency in multi-parameter flow cytometry (Immunostaining, acquisition, and analysis)
• Hands-on expertise in T-cell functional characterization assays such as in vitro cytotoxicity, proliferation, and cytokine measurement
• Molecular engineering and construct/plasmid design
• Experience with IO biologics (T-cell engagers, bispecific antibodies)
• Ability and motivation to drive projects to completion in a team environment

Pay

The annual base pay for this position ranges from $118K to $178K.

Schedule

Our positions offer eligibility for various incentives—opportunities to receive short-term incentive bonuses, equity-based awards for salaried roles, and commissions for sales roles.

Benefits

• Qualified retirement programs
• Paid time off (i.e., vacation, holiday, and leaves)
• Health, dental, and vision coverage in accordance with the terms of the applicable plans

About Our Gaithersburg Oncology Hub

This campus employs more than 3,500 authorities in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most ground-breaking technology and lab spaces, all designed to inspire collaboration and cross-functional science.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being daring - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering innovative methods, and bringing unexpected teams together.