Senior Scientist, Antibody Engineering & Discovery (BMD)

About the role

The BioMedicine Design (BMD) group at Pfizer Torrey Hills site is seeking a highly motivated Senior Scientist (R4) to contribute to the discovery and engineering of next-generation biologics, with an emphasis on multispecific antibodies like immune cell engagers (TCEs). This role will leverage yeast and phage display platforms to drive antibody discovery and optimization and will contribute to format engineering across immuno-oncology portfolios.

Responsibilities

• Design and execute antibody discovery/engineering campaigns using yeast/phage display technologies, including library construction, screening, and hit identification
• Implement innovative strategies for the design and development of next-generation multispecific biologics
• Leverage cross-functional data to define and drive molecular design and optimization strategies, collaborate across internal teams and external partners to drive efficient decision-making and program advancement
• Contribute to platform development and continuous improvement of display technologies and screening strategies
• Clearly communicate results and scientific insights to project teams and leadership
• Stay informed with literature and scientific advancement in the biologics discovery and engineering field
• Maintain rigorous documentation and uphold high standards of scientific quality and data integrity

Qualifications

• Ph.D. in Immunology, Molecular Biology, Protein Engineering, Chemical and Biomolecular Engineering or a related field, with postdoctoral training
• Demonstrated strong hands-on expertise in yeast display for antibody discovery and/or engineering, with creative problem-solving and solid analytical skills. Extensive technical skills in protein expression, purification and molecular biology. Strong publication record in peer-reviewed journals, reflecting scientific innovation and impact
• Prominent ability to independently design experiments, analyze complex datasets, and drive scientific decisions
• Excellent work ethic, with strong ownership, attention to detail, and a commitment to high-quality execution

Attributes

• Strong scientific curiosity and problem-solving mindset
• Ability to operate effectively in a fast-paced, collaborative environment
• Clear and concise communication skills, with the ability to influence cross-functional decisions
• Commitment to BMD culture: collaboration, scientific excellence, and delivery for portfolio impact ("we better")

Pay

The annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share-based long-term incentive program.

Schedule

On Premise

Benefits

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.