Senior Scientist, Antibody Discovery

About the role

We are on a quest for cures and are committed to being the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines. We are seeking a highly motivated, energetic, and skilled Senior Scientist to join the Discovery Biologics team in South San Francisco.

Responsibilities

• Design, execute, and lead antibody discovery campaigns using single B-cell discovery workflows.
• Identify and implement opportunities to reduce timelines, improve throughput, and increase operational efficiency.
• Represent the antibody discovery group on multidisciplinary project teams and provide scientific leadership on discovery strategy, screening plans, and candidate progression.
• Stay current with emerging scientific and technological advances relevant to antibody discovery and single-cell platforms.
• Contribute to the external scientific visibility of the Discovery Biologics team through publications, presentations, and scientific engagement.

Qualifications

• Education: Bachelor's (with 7+ years), Master's (with 4+ years) or Ph.D. in Biology, Biochemistry or related discipline and relevant experience.
• Required Experience and Skills:
  • Strong technical expertise with the 10x Genomics Single Cell 5′ V(D)J workflow for antigen-specific antibody isolation, including sample preparation, B-cell sorting, and library generation and/or hands-on experience with single cell antibody platform/s to screen immunized B-cell repertoires, including recovery of antigen-specific antibody sequences.
  • Strong hands-on laboratory skills in cell culture, molecular biology, high-throughput screening, assay development, and flow cytometry.
  • Significant hands-on experience in antibody discovery, with specific expertise in in vivo immunization-based discovery approaches using single B-cell screening and sequencing.
  • Excellent communication, collaboration, and cross-functional partnership skills.
  • Demonstrated ability to manage multiple projects and competing priorities while maintaining scientific rigor and attention to detail.
  • Proven success working in a fast-paced, deadline-driven environment.
  • Highly motivated and collaborative scientist with a strong sense of ownership, urgency, and adaptability.
  • Established external reputation through publications, presentations, and/or scientific community engagement.
  • Champion for a varied and inclusive culture.
• Preferred Experience and Skills:
  • Experience with next-generation sequencing approaches and related data interpretation in antibody discovery workflows is preferred (including 10x Genomics data).
  • Experience managing antibody discovery campaigns.

Requirements

• As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.
• We are committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.
• Please click here if you need an accommodation during the application or hiring process.

Pay

The salary range for this role is $131,400.00 - $206,800.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

Schedule

Shift 1st - Day