Senior/Executive Director, Business Operations

About the role

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.

Responsibilities

• Strategic Planning and Execution
  • Shape and communicate the company's strategic direction through well-structured presentations that guide prioritization and resource allocation
  • Lead strategic analyses for program evaluation, including discounted cash flow modeling, and secondary research (e.g., analogs research, epidemiology, claims data analysis)
  • Prepare a strategy to guide the successful US commercialization of encaleret
• Stakeholder Communication
  • Develop and deliver executive-level presentations that effectively communicate strategic insights, corporate initiatives, and market analyses
  • Create high-quality visual materials for partnership dialogue, Board of Directors meetings, investor discussions & communications, and internal alignment efforts
  • Ensure presentations are tailored to the audience, synthesizing technical and business content into clear, concise, and actionable messaging
  • Present and discuss findings of strategic analyses to a variety of audiences, including the Calcilytix team, leadership, and investors
  • Support corporate development and partnering strategy to ensure that Encaleret can be accessed by eligible patients worldwide
• Operational Excellence
  • Oversee budget planning initiatives and ownership of long-term lifecycle planning
• Cross-functional Partnership
  • Collaborate with R&D, Regulatory, Finance, Commercial, and Operations to ensure holistic strategy development
  • Collaborate with functional experts as a strategic partner to support the clinical and commercial success of Encaleret
  • Collaborate with the BridgeBio commercial team and oversee research in pricing and reimbursement
  • Lead or contribute to special initiatives involving product lifecycle planning, global expansion, or operational efficiency

Requirements

• A higher degree or equivalent, such as an M.B.A., M.D., or Ph.D., is preferred
• 2-5 years of professional experience in management consulting (life sciences preferred), post-Series A investing, investment banking, venture capital, equity research, and/or corporate role in a therapeutics company
• Prior experience contributing to new product commercialization is a plus
• Proven scientific acumen, communication skills, and an analytical mindset
• A passion for helping patients
• Proficiency in financial modeling, particularly DCF models
• Tenure-appropriate understanding of the drug development life science and operating model. Understands how value is created across the lifespan of a molecule from discovery to commercial execution
• Tenure-appropriate understanding of the biotech landscape
• Exceptional written communication and presentation skills

Schedule

This role requires in-office collaboration at least 3-4x per week in our San Francisco or Palo Alto Office.

Pay

The anticipated salary range for candidates for this role who will work in California is $249,000 - $330,000 USD. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, educational background, location of residence, and performance during the interview process.

Benefits

• Financial & Rewards
  • Market-leading compensation
  • 401(k) with employer match
  • Employee Stock Purchase Program (ESPP)
  • Pre-tax commuter benefits (transit and parking)
  • Referral bonus for hired candidates
  • Subsidized lunch and parking on in-office days
• Health & Well-Being
  • 100% employer-paid medical, dental, and vision premiums for you and your dependents
  • Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)
  • Fertility & family-forming benefits
  • Expanded mental health support (therapy and coaching resources)
  • Hybrid work model with flexibility
  • Flexible, “take-what-you-need” paid time off and company-paid holidays
  • Comprehensive paid medical and parental leave to care for yourself and your family
• Skill Development & Career Paths
  • Regular feedback, continuous education, and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching
  • Career pathing through internal mobility and growth opportunities
  • Financial rewards, peer-to-peer recognition, and growth opportunities for strong performance