Senior Director Health Economics Outcomes Research

About the role

Grifols is seeking a visionary and scientifically grounded leader for an industry-leading Global HEOR/RWE team. The successful candidate will partner with cross-functional stakeholders to ensure HEOR/RWE plans and deliverables are scientifically rigorous, decision-relevant, and ready to support clinical studies, payer/HTA engagement, pricing, and reimbursement.

Responsibilities

• Define and own the global HEOR/RWE vision, strategy, and multi-year evidence generation roadmap, ensuring alignment with pipeline, launch, and lifecycle priorities and integration of RWE into value demonstration, HTA engagement, and pricing and reimbursement decision-making.
• Provide senior scientific leadership to cross-functional teams and executive management, serving as a trusted advisor on program risk, opportunity, and strategic trade-offs.
• Define the enterprise strategy for the use of RWE in regulatory, payer, and HTA contexts, serving as the senior HEOR/RWE partner to Regulatory Affairs and global health authorities.
• Lead integrated evidence planning with cross-functional stakeholders to align research questions, endpoints, and study designs with payer/HTA requirements and value hypotheses.
• Establish and govern Global HEOR/RWE standards, processes, and quality frameworks to ensure scientific rigor, consistency, compliance, and decision-grade evidence across deliverables.
• Lead the design, execution, and interpretation of HEOR/RWE studies (e.g., comparative effectiveness, burden of illness, treatment patterns, PRO/COA, registries, claims/EHR analyses, and economic models), ensuring fit-for-purpose methods and clear decision recommendations.
• Ensure evidence is translated into access-enabling deliverables (e.g., global value dossier/AMCP dossier content and support for HTA submissions), aligned to stakeholder needs across priority markets.
• Oversee the end-to-end HEOR/RWE portfolio (book of work), including prioritization, resourcing, budgets, timelines, performance metrics, and proactive risk management.
• Lead the publication and dissemination strategy for HEOR/RWE projects to strengthen scientific credibility and visibility in priority disease areas.
• Monitor evolving methodologies and policy trends across payers, HTA bodies, and RWE to inform standards, training, and evidence strategy updates.
• Lead and develop a globally-distributed HEOR/RWE team (health economists, outcomes researchers, epidemiologists, statisticians/analysts, and scientific communications partners), including hiring, coaching, performance management, and succession planning.
• Build and scale operating capabilities (data strategy, analytics, vendor ecosystem, tools, and training) to support pipeline growth and lifecycle evidence needs.
• Ensure excellence in scientific quality, documentation, and compliance (e.g., protocol/SAP governance, data privacy, vendor oversight, and audit readiness) across HEOR/RWE activities.
• Drive continuous improvement of HEOR/RWE operations, including ways of working, tools, and training to increase speed and quality of delivery.
• Partner with key stakeholders (Clinical Development, Regulatory, Biostatistics, Medical Affairs, Pharmacovigilance, Commercial/Market Access, Legal, Finance, and Global Program Teams) to align evidence plans with development and access priorities.
• Foster a collaborative, matrix-based culture that promotes transparency, scientific rigor, and shared ownership of outcomes.
• Represent HEOR/RWE in internal governance bodies and executive forums, communicating evidence strategy, insights, and implications for access and value positioning.
• Develop and maintain strategic external relationships (payers, HTA bodies, KOLs, scientific societies, and patient advocacy groups) to inform evidence standards and enhance value communication.

Requirements

• Education: MD, MD/PhD, PhD, PharmD, or equivalent advanced scientific/medical degree.
• Experience: Typically 15+ years of experience in HEOR/RWE within pharma, biotech, or medical devices.
• Knowledge: Deep knowledge of outcomes research and RWE methodologies (study design, statistics, data sources, and implementation).
• Skills: Proven experience managing vendors, budgets, and building productive partnerships with internal stakeholders and external experts/KOLs.
• Communication: Excellent communication skills, with the ability to translate complex analyses into clear recommendations for senior stakeholders.
• Leadership: Demonstrated leadership in matrixed environments, including the ability to direct work across functions to deliver shared objectives.
• Experience: Experience across multiple therapeutic areas; experience in Neurology, Immunology, Hematology, Coagulation, and/or Critical Care is preferred. Experience across multiple therapeutic areas and development modalities is strongly preferred.
• Attributes: Credible, team-oriented HEOR/RWE leader with executive presence and a strategic mindset. Collaborative, inclusive leader who inspires teams and encourages innovation. Comfortable navigating complexity, ambiguity, and change. Strong communicator with the ability to influence at senior and executive levels. Hands-on, pragmatic, and outcomes-driven, aligned with Grifols' culture and values.

Qualifications/Education Requirements

• To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skills, education, and/or ability required.
• Education: MD, MD/PhD, PhD, PharmD, or equivalent advanced scientific/medical degree.
• Experience: Typically 15+ years of experience in HEOR/RWE within pharma, biotech, or medical devices.
• Knowledge: Deep knowledge of outcomes research and RWE methodologies (study design, statistics, data sources, and implementation).
• Skills: Proven experience managing vendors, budgets, and building productive partnerships with internal stakeholders and external experts/KOLs.
• Communication: Excellent communication skills, with the ability to translate complex analyses into clear recommendations for senior stakeholders.
• Leadership: Demonstrated leadership in matrixed environments, including the ability to direct work across functions to deliver shared objectives.
• Experience: Experience across multiple therapeutic areas; experience in Neurology, Immunology, Hematology, Coagulation, and/or Critical Care is preferred. Experience across multiple therapeutic areas and development modalities is strongly preferred.
• Attributes: Credible, team-oriented HEOR/RWE leader with executive presence and a strategic mindset. Collaborative, inclusive leader who inspires teams and encourages innovation. Comfortable navigating complexity, ambiguity, and change. Strong communicator with the ability to influence at senior and executive levels. Hands-on, pragmatic, and outcomes-driven, aligned with Grifols' culture and values.