Senior Director, Business Process Transformation

About the role

The Senior Director of Business Process Transformation is responsible for architecting and advancing MSD's digital thread—the governed, end-to-end flow of product, process, service and quality data connecting R&D, engineering, manufacturing, quality, regulatory, supply chain, and commercial operations—and for leading the enterprise-wide redesign of the business processes that span this value chain.

Responsibilities

• Serve as a strategic thought partner to executive leadership, translating long-range business objectives into an integrated process roadmap, defining target-state operating models, leading cross-functional change initiatives, and governing value realization.
• Set process architecture standards, drive continuous improvement, and measure transformation outcomes against quantifiable business KPIs.
• Define and own MSD's digital thread vision, strategy, and reference architecture—linking product definition to manufacturing execution to service and commercial feedback.
• Lead end-to-end business process transformation programs spanning the PLM, ERP, and MES value chains, including product design release, engineering change, item and BOM management, planning, procurement, manufacturing execution, inventory, quality, regulatory, and order-to-cash.
• Build and maintain MSD's enterprise process architecture—capability maps, value streams, end-to-end process models, and target-state operating models—that inform investment decisions and transformation sequencing.
• Translate process requirements into platform capability requirements and hold the integration teams accountable.
• Lead strategic business process reengineering initiatives using Lean, Six Sigma, business process management (BPM), and design thinking methods to deliver measurable operational and commercial outcomes.
• Direct the business case, roadmap, and value realization for enterprise transformation programs—including stage-gate governance, outcome KPIs, benefits tracking, and executive reporting.
• Build and lead a high-performing team of process architects, business analysts, and transformation leaders; develop functional, analytical, and change leadership capabilities across the team and broader organization.
• Collaborate with Engineering, Manufacturing, Supply Chain, Quality, Regulatory, Commercial, and Finance leadership to co-design integrated processes and translate business outcomes into capability requirements.
• Ensure comprehensive documentation of process architecture, target-state designs, transformation playbooks, and governance artifacts.
• Collaborate with Enterprise Platforms, Software Engineering, IT Infrastructure, and Cybersecurity teams to align process designs with secure, scalable, and compliant system implementations.
• Stay current with emerging transformation methodologies, enterprise architecture frameworks, and industry benchmarks relevant to life sciences and regulated manufacturing.
• Ensure that transformation artifacts—process designs, change documentation, training materials, validation evidence—are compliant with GxP, 21 CFR Part 11, ISO 9001, and ISO 27001 expectations in partnership with Quality, Regulatory, and regulated services functions.
• Define and track digital transformation and process excellence KPIs—cycle time, first-pass yield, process automation rate, data quality, user adoption, cost-to-serve, and transformation ROI—and drive data-informed improvement.

Requirements

• Bachelor's degree in Engineering, Business, Computer Science, or a related discipline, or equivalent work experience; advanced degree (Master’s or MBA or PhD) preferred.
• A minimum of fifteen years of progressive experience in business process transformation, enterprise/business architecture, or digital transformation leadership, preferably in a regulated manufacturing environment.
• A minimum of five years leading enterprise-scale transformation programs that span multiple business functions and enterprise platforms.
• Proven experience defining and executing digital thread or model-based enterprise strategies that link product definition to manufacturing execution to service and commercial feedback.
• Demonstrated working knowledge of PLM, ERP, and MES platforms—specifically Siemens Teamcenter, Oracle JD Edwards (JDE), and SAP S/4HANA—with fluency in their capabilities, integration patterns, and data models.
• Deep hands-on configuration ownership is not required; strong fluency in the capabilities, integration patterns, and data models is required.
• Demonstrated experience leading Lean, Six Sigma, or business process management initiatives that have delivered measurable operational and financial outcomes.
• Demonstrated experience leading enterprise change management for multi-year transformation programs, including executive stakeholder alignment and adoption strategy.
• Certification in Lean Six Sigma (Black Belt or higher), business process management (e.g., CBPP), enterprise architecture (e.g., TOGAF), business architecture (e.g., CBA), or change management (e.g., Prosci ADKAR) is preferred; PMP is a plus.
• Implementation experience working across multiple departments with customers at various organizational levels.
• Consultant experience on implementations for Life Science organizations preferred.

Qualifications

• Deep understanding of digital thread principles, model-based enterprise concepts, and end-to-end process architecture in a regulated manufacturing context.
• Recognized thought leader with a future-focused perspective on Industry 4.0, AI-enabled process automation, closed-loop quality, digital twin, and the evolving role of enterprise platforms in life sciences.
• Expert knowledge of PLM, ERP, and MES business domains—product lifecycle, engineering change, planning, procurement, manufacturing execution, quality, regulatory, and order-to-cash—with fluency to translate across them without owning platform configuration.
• Strong business architecture and process modeling skills, including BPMN, value stream mapping, capability mapping, and target operating model design.
• Mastery of Lean, Six Sigma, and business process management methodologies and the ability to select and sequence them appropriately.
• Superior leadership skills with demonstrated ability to influence across functions, lead through ambiguity and change, and establish accountabilities without direct authority.
• Strong organizational change management capability, including stakeholder engagement, communications strategy, training design, and adoption measurement.
• Organizational, program, and priority management skills for planning, executing, and following up on multi-year transformation portfolios in order to meet established deadlines and value-realization targets.
• Demonstrated ability to develop executive-grade business cases, measure benefits realization, and hold transformation programs accountable to quantified KPIs.
• Demonstrated critical thinking and analytical skills, as well as the ability to handle complex situations and demonstrate sound judgment and problem-solving.
• Excellent communication and storytelling skills with the ability to organize, present, and articulate ideas both verbally and in writing, including the ability to influence at the executive level and simplify complex transformation concepts for non-technical audiences.
• Ability to effectively communicate risks, dependencies, and results that impact transformation timelines, business outcomes, and compliance posture.

Skills and Abilities

• Deep understanding of digital thread principles, model-based enterprise concepts, and end-to-end process architecture in a regulated manufacturing context.
• Recognized thought leader with a future-focused perspective on Industry 4.0, AI-enabled process automation, closed-loop quality, digital twin, and the evolving role of enterprise platforms in life sciences.
• Expert knowledge of PLM, ERP, and MES business domains—product lifecycle, engineering change, planning, procurement, manufacturing execution, quality, regulatory, and order-to-cash—with fluency to translate across them without owning platform configuration.
• Strong business architecture and process modeling skills, including BPMN, value stream mapping, capability mapping, and target operating model design.
• Mastery of Lean, Six Sigma, and business process management methodologies and the ability to select and sequence them appropriately.
• Superior leadership skills with demonstrated ability to influence across functions, lead through ambiguity and change, and establish accountabilities without direct authority.
• Strong organizational change management capability, including stakeholder engagement, communications strategy, training design, and adoption measurement.
• Organizational, program, and priority management skills for planning, executing, and following up on multi-year transformation portfolios in order to meet established deadlines and value-realization targets.
• Demonstrated ability to develop executive-grade business cases, measure benefits realization, and hold transformation programs accountable to quantified KPIs.
• Demonstrated critical thinking and analytical skills, as well as the ability to handle complex situations and demonstrate sound judgment and problem-solving.
• Excellent communication and storytelling skills with the ability to organize, present, and articulate ideas both verbally and in writing, including the ability to influence at the executive level and simplify complex transformation concepts for non-technical audiences.
• Ability to effectively communicate risks, dependencies, and results that impact transformation timelines, business outcomes, and compliance posture.

Benefits

At MSD, we offer a comprehensive benefits package to support our employees' well-being and financial security. In addition to competitive salaries, our benefits include medical, dental, and vision coverage, along with prescription benefits. We provide a 401(k) plan with company matching, flexible spending accounts, and company-paid short- and long-term disability insurance as well as group life and accidental death and dismemberment insurance. Our offerings also encompass paid vacation, paid sick leave, paid holidays, and paid parental leave, along with an employee assistance program. Additional voluntary perks include a fitness club membership contribution, pet insurance, identity theft protection, home and auto insurance discounts, and optional supplemental life insurance.

Pay

The annual base salary for this position ranges from $174,100 to $272,050. This salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate’s knowledge, skills, abilities, education and experience. Employees may qualify for a discretionary or non-discretionary bonus in addition to their base salary. These annual bonuses are intended to recognize individual performance and enable employees to benefit from the Company's overall success.

Schedule

This position is performed in a traditional office environment.