Scientist III - Protein Characterization & LC-MS

Randstad Life Sciences is seeking a Scientist III to join an elite Analytical Development team in Worcester, MA. In this full-time, on-site contract role, you will perform high-impact analytical characterization of therapeutic proteins, supporting innovative biologics from discovery through process development.

Responsibilities

• Perform LC-MS experiments for intact/reduced mass analysis and peptide mapping to evaluate protein sequences and post-translational modifications.
• Execute separation and fractionation assays using HPLC/UPLC and AKTA systems.
• Perform biophysical characterization methods (e.g., DSC) and raw material analyses using vibrational spectroscopy.
• Design and execute robust experiments for analytical method development, troubleshooting, and investigative studies.
• Generate reliable data, maintain detailed electronic laboratory notebooks (ELN), and author technical characterization reports.

Requirements

• Bachelor's (5+ years experience) or Master's (2+ years experience) in Chemistry, Biology, Biochemistry, or related technical discipline.
• Proven experience in a biotech/pharmaceutical industry setting.
• Hands-on expertise with protein mass spectrometry, liquid chromatography (HPLC/UPLC), and fractionation (AKTA).
• Strong foundational understanding of protein structure, post-translational modifications, and characterization assays.
• Excellent technical writing, verbal communication, and organizational skills.

Qualifications

• Experience using bioinformatics software to process and analyze mass spectrometry data (preferred).
• Familiarity with vibrational spectroscopy (IR, NIR, Raman) and multivariate analysis (preferred).

Skills

• Biology
• Chemistry
• High Pressure Liquid Chromatography (HPLC)
• Liquid Chromatography (LC)
• Mass Spectrometry (MS)
• Good Laboratory Practices (GLP)
• Good Manufacturing Practices (GMP)

Pay

$58.00 - 68.25 per hour

Benefits

• Medical, prescription, dental, and vision insurance
• AD&D and life insurance
• Short-term disability
• 401K plan

Schedule

9 to 5, full-time, on-site

Location: Worcester, Massachusetts

Job type: Contract