Jobs · OTHR · Pennsylvania

Scientist, Cell Biology

Kite Pharma · Philadelphia, PA · Yesterday
OTHR$133k–$172k/yrFull-time

About the role

We’re dedicated to developing treatments and pioneering personalized CAR T-cell therapies that change the paradigm of cancer care. Join Kite to advance cancer therapies and help shape the future of our business and medical science. As a people leader or future leader, you’ll drive our culture and create an environment where every employee feels included, developed, and empowered.

Responsibilities

  • Design, plan, and execute experiments (in vivo and in vitro) with limited guidance against project timelines, goals, and study endpoints; coordinate day-to-day study logistics as needed.
  • Lead and execute hands-on in vivo mouse studies including routine animal handling, dosing/injections (e.g., intravenous tail vein and intraperitoneal, as applicable), IVIS imaging support, blood collection, tissue harvest/dissection, and sample processing in accordance with approved protocols and SOPs.
  • Design, perform, and optimize complementary in vitro experiments (e.g., routine mammalian cell culture, primary human cell handling, and cell-based assays) to evaluate experimental constructs and connect in vitro findings to in vivo outcomes; engineer, culture, and characterize CAR T cells in vitro as needed.
  • Conduct immunophenotyping and biomarker readouts, including flow cytometry, analyze results, and translate findings into actionable next steps.
  • Set up and run ELISA and other plate-based assays, analyze and interpret data with attention to quality and reproducibility, and present results in team meetings.
  • Independently troubleshoot and optimize in vivo procedures and in vitro assays using critical thinking and scientific judgment to reduce variability and improve robustness.
  • Collaborate with cross-functional partners to align study plans, sample logistics, and data outputs with program objectives; summarize findings in clear technical updates and presentations.
  • Develop technical solutions to complex problems requiring ingenuity and creativity; troubleshoot and optimize methods and workflows to improve scientific outcomes relating to in vivo and ex vivo studies.
  • Contribute to a positive, high-performing team culture by sharing best practices and mentoring/training junior staff in mouse study execution, assay performance, data analysis, and laboratory organization.
  • Maintain mammalian cell lines and primary human cells using sterile technique in a biosafety cabinet.
  • Organize and maintain experimental work in an electronic lab notebook.
  • Occasional weekend work might be required.

Requirements

  • BS with 6+ years of relevant experience OR MS with 4+ years of relevant experience OR PhD/PharmD with 0+ years of relevant experience.

Qualifications

  • Degree in Immunology, Virology, or Cell Biology is preferred.
  • 4+ years experience in an academic or industry setting is preferred.
  • Prior experience with mouse handling and interventions including intravenous (tail vein) and intraperitoneal injections are highly preferred.
  • Demonstrated critical thinking and scientific judgment, with a track record of independently troubleshooting and optimizing methods to deliver high-quality, reproducible data.
  • Ability to flex seamlessly between hands-on mouse studies and bench-based in vitro experiments, adapting daily priorities to meet program needs and study schedules.
  • Experience with mammalian cell culture and primary cells is ideal.
  • Strong organizational skills, attention to detail, and commitment to high-quality data generation.
  • Demonstrated ability to work under minimal direction on moderately complex assignments; independently determines and develops approaches, with most work reviewed minimally.
  • Proven experience planning and executing research experiments independently and applying scientific judgment to define next steps based on outcomes.
  • Experience contributing to written scientific outputs (e.g., reports, publications, patents, or external presentations).
  • Established record of scientific research excellence in academia and/or industry.
  • Experience leading components of cross-functional projects and mentoring junior colleagues.
  • Proficiency in Excel, PowerPoint, Prism, and other programs to create and distribute reports and key information.
  • Excellent interpersonal, written, and verbal communication skills.
  • Ability to work onsite in a laboratory environment.

Pay

The salary range for this position is $133,195.00 - $172,370.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package.

Benefits

  • Company-sponsored medical, dental, vision, and life insurance plans.

For additional benefits information, visit: Gilead Careers - Compensation, Benefits, and Wellbeing.

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