Scientist -Antibody Technologies - Exp in Protein expression, Tissue culture, Molecular biology

Job Description

We are seeking a highly motivated and organized Scientist III to contribute to the discovery and development of monoclonal antibodies in our Antibody Discovery team. This individual will be responsible for working in a dynamic team environment and be a contributor to multiple work streams, including but not limited to protein expression and purification, cell-line engineering, and testing new antibodies for use in flow cytometry application.

Duties And Responsibilities

• Responsible for transfection and expression of antibodies and recombinant proteins using multiple cell lines and expression systems.
• Responsible for sterile cell culture of multiple cell lines using aseptic technique for expression and flow testing.
• Responsible for the execution of experiments with varying complexity using advanced molecular biology techniques.
• Responsible for the execution of experiments with varying complexity using multi-color Flow Cytometry.
• Analyze data using FCS Express and FlowJo software, report test results including completion of all required documentation and database entries as required by protocols and SOPs.
• Day-to-day problem solving and cross-functional team-based activities to ensure that daily operations and timelines are met.
• Independently analyze own research data, solve problems with minimal guidance and effectively plan follow up experiments.
• Will be expected to efficiently prioritize individual workload.
• Involvement with scheduling, operational and maintenance duties required within the laboratory.

Knowledge And Skills

• Protein expression using various systems including but not limit to mammalian cells, insect cells, and bacteria.
• Proficient with aseptic technique and cell-culture techniques.
• Protein purification with liquid chromatography and quality assurance using various analytical methods.
• Preferred: Familiarity with assay automation and automated liquid handlers.
• Preferred: Experience with cell line engineering.
• Preferred: Hand-on experience with Flow Cytometry and the ability of analyzing flow data.
• Effective interpersonal skills and ability to work in a cross-functional team-oriented environment to achieve organizational goals.
• Effective written and oral communication skills.
• Demonstrated ability to follow established policies and procedures.
• Demonstrated ability to keep neat, accurate, and complete records.
• Demonstrated ability to follow established policies and procedures.
• Demonstrated ability to follow established policies and procedures.
• Demonstrated ability to follow established policies and procedures.

Education And Experience

• A Bachelor’s or Master of Science degree in cellular or molecular biology, immunology, cell biology or related scientific discipline and a minimum of 3-6 years of laboratory experience required.
• Protein expression, molecular biology and/or tissue culture experience required.