Research Assistant Professor in the Department of Neurosurgery at the Children's Hospital of Philadelphia

Research Focus

Expertise is required in the specific area of molecular and cancer biology, or closely related fields with a strong record in advanced molecular and cell biology methods, multi-omic profiling, and next-generation sequencing.

Requirements

• Demonstrated expertise in development and application of patient-derived in vitro and in vivo disease tissue culture models for preclinical research and clinical precision medicine applications.
• Ph.D. or M.D./Ph.D. degree.
• Experience building and leading biobanking programs, overseeing biospecimen governance, and generating high-quality molecular data, with experience working with archived and liquid biopsy specimens.
• C competence in multi-omic data integration, large-scale data curation, and adherence to modern data governance and reproducibility standards.
• Demonstrated leadership in cross-departmental and cross-institutional research collaborations, success securing extramural funding, and a strong record of mentoring and directing interdisciplinary laboratory teams.

Responsibilities

• Advancing a personalized tumor-modeling program using patient-derived organoids, cell lines, and xenografts to support functional precision medicine, drug testing, and mechanistic discovery.
• Leading a multi-investigator research environment, integrating multi-omics and imaging datasets for biomarker discovery.
• Driving large-scale, cross-institutional biobanking, data-generation and analysis initiatives.
• Contributing to high-impact publications and grant proposals.
• Partnering with clinical teams to translate laboratory findings into therapeutic insights.