Jobs · Art & Creative · New York

Associate Scientist, Host Cell Protein (HCP) Analytics

BioSpace · Tarrytown, NY · Yesterday
Art & Creative$94k–$153k/yrFull-time

Purification and ELISA Development

Purify polyclonal antibodies from rabbit/goat bleeds immunized with host cell protein antigens, using affinity chromatography and other standard purification workflows.
Optimize and streamline purification protocols to improve yield, purity, reproducibility, and throughput.
Support ELISA method development, qualification, and troubleshooting for HCP detection and quantitation.

Reagent Management

Prepare, aliquot, and manage critical reagents (antibodies, conjugates, standards, buffers) to ensure consistent assay performance.
Document all experimental work in the electronic laboratory notebook (ELN) in accordance with defined procedures and departmental standards, and provide documentation upon request to support internal reviews, tech transfer, or regulatory submissions.

Collaboration

Collaborate cross-functionally with process development, QC, and analytical teams to align on reagent needs and assay performance criteria.
Contribute to continuous improvement of laboratory workflows and best practices.

Environment and Physical Rhythms

This is a hands-on, on-site laboratory role centered on protein purification and immunoassay work, requiring rigorous attention to detail and consistent documentation practices.
Flexibility to work independently, manage multiple tasks in parallel, and collaborate effectively within a team-oriented environment is required.

Qualifications

  • BS/MS in Biochemistry, Chemistry, Molecular Biology, or a related life science discipline
  • Hands-on experience with protein purification (affinity chromatography, e.g., Protein A/G, antigen-affinity columns; AKTA or equivalent FPLC systems preferred)
  • Working knowledge of ELISA and general immunoassay techniques
  • Ability to work independently, manage multiple tasks in parallel, and maintain rigorous attention to detail
  • Excellent written and verbal communication skills; team-oriented mindset

Preferred / Nice-to-Haves

  • Prior ELN experience
  • Strong documentation habits
  • Thriving today. Growing tomorrow

Company Information

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

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