Upstream Manufacturing Technician

About the Role

We are seeking an entry-level to early-career Manufacturing Scientist/Engineer to support upstream operations within antibody-drug conjugate (ADC) manufacturing in an oncology-focused pharmaceutical environment. This role combines hands-on manufacturing with process ownership, continuous improvement, and technical problem-solving.

Responsibilities

• Execute upstream manufacturing processes including:
  • Fermentation
  • Solvent-based recovery
  • Multi-stage chemical synthesis
• Operate within a multi-step drug substance production process.
• Prepare buffers and support in-house reagent production.
• Own and execute assigned processes end-to-end (not shift hand-off based).
• Perform process monitoring, troubleshooting, and optimization.
• Support:
  • Continuous improvement (CI) initiatives
  • Process qualifications and validation
  • Tech transfers and new product introductions
• Author technical documentation, including:
  • Reports
  • SOPs
  • Batch records
• Collaborate with engineering and cross-functional teams.

Work Environment & Schedule

• On-site, 5 days per week.
• Standard hours: ~8:00 AM – 4:30/5:00 PM.
• May require:
  • Early or late shifts (~6+ times/year)
  • Occasional weekend work (~2 times/year)
• Work requires flexibility; employees stay until work is complete.
• Involves use of specialized PPE and handling of cytotoxic materials under strict safety protocols.

Requirements

• Bachelor’s degree in:
  • Biology
  • Chemistry
  • Chemical Engineering
  • Biomedical Engineering
  • Related field
• Strong understanding of scientific principles and laboratory/manufacturing practices.
• Ability to learn complex processes and equipment.

Preferred Qualifications

• Exposure to pharmaceutical or biotech manufacturing.
• Knowledge of GMP environments.
• Strong troubleshooting and analytical skills.

Duration: 06-07 months contract (possible extension). Location: Pearl River, NY 10965.