Senior Scientist- Translational PKPD

About the role

This opening is for a Senior Scientist position in the translational Pharmacokinetics and Pharmacodynamics (tPKPD) department within the Development Sciences division in Genentech Research and Early Development (gRED) unit. The focus of this position is to support the preclinical pharmacokinetic and pharmacodynamics (PKPD) efforts to guide the design, delivery and development of biologics in the Genentech pipeline. Core responsibilities include providing technical support for the PKPD assessment of drug candidates and marketed products and working independently or under the direct supervision of a Scientist.

Responsibilities

• Design, conduct, analyze and interpret all in vitro and in vivo ADME and PKPD studies that are necessary to understand the pharmacology of drug candidates in animals and predict their behavior in humans
• Prepare summary tables and reports for non-clinical studies; may prepare documents for regulatory agencies, including INDs and BLAs under the supervision of a Scientist
• Present data at project teams and department meetings and conferences as appropriate
• Publish innovative PKPD focused research in high quality scientific, technical or medical journals.
• Manage an active laboratory program that supports basic research in PKPD and also supports pipeline projects
• Collaborate with other departments such as Clinical Pharmacology, Research, Bioanalytical Sciences, Safety Assessment, PD Biomarker/OMNI, Antibody Engineering, Non-clinical Biostatistics, Regulatory Affairs, Technical Development, and others
• Participate in compliance and safety related activities.
• Perform other duties, as assigned

Requirements