Senior Scientist I, Small Molecule and Peptide Bioanalysis

AbbVie’s mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience—and products and services in our Allergan Aesthetics portfolio.

About the role

The Quantitative, Translational and ADME Science (QTAS) Department at AbbVie is seeking a highly motivated scientist to join our Non-regulated Bioanalysis Team in North Chicago. In this lab-based role, the ideal candidate will develop and implement LC/MS-based bioanalysis to support pipeline-enabling preclinical studies, provide scientific leadership in developing custom methodology for complex modalities, and evaluate and implement novel technologies and methodologies.

Responsibilities

• Support method development and optimization for quantitative bioanalysis; hands-on experience in peptide extraction, separation, and quantification is required.
• Independently investigate, evaluate, and implement new analytical methodologies and technologies to meet challenging assay requirements while maintaining effective resource utilization.
• Identify, troubleshoot, and provide quick response to address instrument and assay issues.
• Execute operational activities including supporting pipeline-enabling preclinical studies to meet timelines, operate and maintain LC/MS instruments, and maintain accurate study documentation in electronic notebooks.
• Stay current with emerging literature and development of analytical science.
• Mentor junior scientists.

Qualifications

• PhD (0+ years), M.S. (8+ years) or BS (10+ years) in analytical chemistry or related field with relevant academic or industry experience.
• In-depth understanding of LCMS methodology and quantitative science, with a focus on synthetic molecules.
• Hands-on experience with one or more current LC-MS/MS platforms and software; familiarity with automated sample preparation platforms.
• Knowledge of pharmacokinetics with an understanding of both experimental design and data analysis will be a plus.
• Working experience in regulated bioanalysis and/or CRO settings will be a plus.
• Proven ability to work in a team environment and interact with interdisciplinary partners.
• Highly motivated and self-driven with the ability to quickly adapt to shifting priorities.
• Maintain creative and flexible thinking, passionate for learning and solving technical problems.
• Excellent communication and presentation skills and the ability to work effectively both independently and as part of a team.

Skills

• Builds strong relationships with peers and cross-functionally with partners outside of the immediate team to enable higher performance.
• Learns fast, grasps the essence, and can change course quickly when indicated.
• Creates a learning environment, open to suggestions and experiments to drive the science in the field of interest.
• Embraces the ideas of others, nurtures innovation, and manages innovation to reality.

Benefits

• Comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees.
• Eligible to participate in short-term incentive programs.