Senior Scientist I - Peptide Analytical Chemistry

About the role

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio.

Responsibilities

• Lead peptide drug product (DP) formulation development initiatives, providing analytical support for oral and IV peptide formulation platform development; work cross-functionally to advance projects through the development pipeline
• Provide analytical expertise to support diverse peptide formulation approaches, leveraging understanding of formulation technologies, stability science, and analytical characterization specific to peptide therapeutics
• Drive drug product analytical strategy development for peptide oral and IV formulations, including method development, testing procedures, and implementation of analytical control strategies
• Support drug substance characterization and development as needed to inform formulation strategies and contribute to cross-functional DS-DP understanding
• Utilize a range of analytical techniques to conduct research and development studies related to peptide and small-molecule drug substances, active pharmaceutical ingredients, intermediates, starting materials, and impurity profiling
• Independently and autonomously perform laboratory research and method development with minimal supervision, demonstrating high productivity and scientific initiative
• Initiate new areas of investigation that are scientifically meaningful, reliable, and can be directly incorporated into research or development programs
• Formulate conclusions, design follow-on experiments, and process, interpret, and visualize data based on multidisciplinary findings to facilitate project team decision-making
• Develop, test, and implement analytical control strategies to support advancement of drug discovery and development candidates
• Routinely demonstrate scientific initiative, creativity, and continuous improvement - never satisfied with the status quo, always raising the bar
• Utilize a range of analytical techniques to conduct research and development studies related to peptide and small-molecule drug substances, especially therapeutic peptides, to further the understanding of emerging cGMP manufacturing processes

Requirements

• Bachelor's, Master's, or PhD in Analytical Chemistry or Pharmaceutical Sciences (with strong Analytical focus)
• Typically with minimum 10 (BS), 8 (MS), or 0 - 2 (Ph.D.) years related industry experience
• Strong technical background in analytical chemistry for peptides and small molecules
• Proficiency in chromatographic techniques (HPLC/UHPLC, SEC, chiral separation), high-resolution mass spectrometry (HRMS), LC-MS/MS, and sample preparation for complex matrices
• Practical knowledge of organic structure, functional groups, and modern spectroscopic techniques applied to peptide and small-molecule analysis
• Experience in peptide characterization, degradation pathway understanding, and formulation science is highly preferred
• Excellent analytical problem-solving skills with strong critical thinking capability
• Capable of independently developing, optimizing, and troubleshooting complex analytical methods
• Demonstrates resilience when facing challenges, learns rapidly, and iterates quickly
• Self-motivated, hard-working, and detail-oriented
• Demonstrates genuine curiosity and desire to learn and advance technical capabilities
• Takes proactive ownership beyond assigned scope when it advances scientific understanding or program goals
• Raises the bar continuously - never satisfied with the status quo
• Demonstrates high-quality written and oral communication skills with ability to translate complex analytical data into clear, compelling narratives
• Actively engages in cross-functional discussions, asks strategic questions that advance team understanding, and presents findings effectively to diverse audiences
• Builds strong relationships and works effectively with interdisciplinary teams across diverse backgrounds
• Demonstrates ability to own technical strategy, mentor junior scientists, and proactively identify gaps and bring solutions to the table
• Shows history of proposing novel analytical approaches and contributing to intellectual capital (publications, presentations, IP)
• Creates a learning environment open to suggestions and experimentation for continuous improvement, inspiring curiosity, rigor, and a learning mindset in others

Qualifications

• Bachelor's, Master's, or PhD in Analytical Chemistry or Pharmaceutical Sciences (with strong Analytical focus)
• Typically with minimum 10 (BS), 8 (MS), or 0 - 2 (Ph.D.) years related industry experience
• Strong technical background in analytical chemistry for peptides and small molecules
• Proficiency in chromatographic techniques (HPLC/UHPLC, SEC, chiral separation), high-resolution mass spectrometry (HRMS), LC-MS/MS, and sample preparation for complex matrices
• Practical knowledge of organic structure, functional groups, and modern spectroscopic techniques applied to peptide and small-molecule analysis
• Experience in peptide characterization, degradation pathway understanding, and formulation science is highly preferred
• Excellent analytical problem-solving skills with strong critical thinking capability
• Capable of independently developing, optimizing, and troubleshooting complex analytical methods
• Demonstrates resilience when facing challenges, learns rapidly, and iterates quickly
• Self-motivated, hard-working, and detail-oriented
• Demonstrates genuine curiosity and desire to learn and advance technical capabilities
• Takes proactive ownership beyond assigned scope when it advances scientific understanding or program goals
• Raises the bar continuously - never satisfied with the status quo
• Demonstrates high-quality written and oral communication skills with ability to translate complex analytical data into clear, compelling narratives
• Actively engages in cross-functional discussions, asks strategic questions that advance team understanding, and presents findings effectively to diverse audiences
• Builds strong relationships and works effectively with interdisciplinary teams across diverse backgrounds
• Demonstrates ability to own technical strategy, mentor junior scientists, and proactively identify gaps and bring solutions to the table
• Shows history of proposing novel analytical approaches and contributing to intellectual capital (publications, presentations, IP)
• Creates a learning environment open to suggestions and experimentation for continuous improvement, inspiring curiosity, rigor, and a learning mindset in others