Senior Scientist I - Peptide Analytical Chemistry

About the role

Lead peptide drug product (DP) formulation development initiatives, providing analytical support for oral and IV peptide formulation platform development; work cross-functionally to advance projects through the development pipeline.

Responsibilities

• Provide analytical expertise to support diverse peptide formulation approaches, leveraging understanding of formulation technologies, stability science, and analytical characterization specific to peptide therapeutics.
• Drive drug product analytical strategy development for peptide oral and IV formulations, including method development, testing procedures, and implementation of analytical control strategies.
• Support drug substance characterization and development as needed to inform formulation strategies and contribute to cross-functional DS-DP understanding.
• Utilize a range of analytical techniques to conduct research and development studies related to peptide and small-molecule drug substances, active pharmaceutical ingredients, intermediates, starting materials, and impurity profiling.
• Independently and autonomously perform laboratory research and method development with minimal supervision, demonstrating high productivity and scientific initiative.
• Initiate new areas of investigation that are scientifically meaningful, reliable, and can be directly incorporated into research or development programs.
• Formulate conclusions, design follow-on experiments, and process, interpret, and visualize data based on multidisciplinary findings to facilitate project team decision-making.
• Demonstrate scientific initiative, creativity, and continuous improvement - never satisfied with the status quo, always raising the bar.
• Apply analytical separation and detection modes for complex impurity profiling of pharmaceutical products, especially therapeutic peptides, to further the understanding of emerging cGMP manufacturing processes.

Requirements

• Strong technical background in analytical chemistry for peptides and small molecules.
• Practical knowledge of organic structure, functional groups, and modern spectroscopic techniques applied to peptide and small-molecule analysis.
• Experience in peptide characterization, degradation pathway understanding, and formulation science is highly preferred.
• Excellent analytical problem-solving skills with strong critical thinking capability. Capable of independently developing, optimizing, and troubleshooting complex analytical methods.
• Demonstrates resilience when facing challenges, learns rapidly, and iterates quickly.
• Self-motivated, hard-working, and detail-oriented. Demonstrates genuine curiosity and desire to learn and advance technical capabilities.
• Takes proactive ownership beyond assigned scope when it advances scientific understanding or program goals. Raises the bar continuously - never satisfied with the status quo.
• Demonstrates high-quality written and oral communication skills with ability to translate complex analytical data into clear, compelling narratives. Actively engages in cross-functional discussions, asks strategic questions that advance team understanding, and presents findings effectively to diverse audiences.
• Builds strong relationships and works effectively with interdisciplinary teams across diverse backgrounds.
• Demonstrates ability to own technical strategy, mentor junior scientists, and proactively identify gaps and bring solutions to the table. Shows history of proposing novel analytical approaches and contributing to intellectual capital (publications, presentations, IP).
• Creates a learning environment open to suggestions and experimentation for continuous improvement, inspiring curiosity, rigor, and a learning mindset in others.

Qualifications

• Bachelor's, Master's, or PhD in Analytical Chemistry or Pharmaceutical Sciences (with strong Analytical focus)
• Typically with minimum 10 (BS), 8 (MS), or 0 - 2 (Ph.D.) years related industry experience.

Skills

• Strong technical background in analytical chemistry for peptides and small molecules.
• Practical knowledge of organic structure, functional groups, and modern spectroscopic techniques applied to peptide and small-molecule analysis.
• Experience in peptide characterization, degradation pathway understanding, and formulation science is highly preferred.
• Excellent analytical problem-solving skills with strong critical thinking capability. Capable of independently developing, optimizing, and troubleshooting complex analytical methods.
• Demonstrates resilience when facing challenges, learns rapidly, and iterates quickly.
• Self-motivated, hard-working, and detail-oriented. Demonstrates genuine curiosity and desire to learn and advance technical capabilities.
• Takes proactive ownership beyond assigned scope when it advances scientific understanding or program goals. Raises the bar continuously - never satisfied with the status quo.
• Demonstrates high-quality written and oral communication skills with ability to translate complex analytical data into clear, compelling narratives. Actively engages in cross-functional discussions, asks strategic questions that advance team understanding, and presents findings effectively to diverse audiences.
• Builds strong relationships and works effectively with interdisciplinary teams across diverse backgrounds.
• Demonstrates ability to own technical strategy, mentor junior scientists, and proactively identify gaps and bring solutions to the table. Shows history of proposing novel analytical approaches and contributing to intellectual capital (publications, presentations, IP).
• Creates a learning environment open to suggestions and experimentation for continuous improvement, inspiring curiosity, rigor, and a learning mindset in others.

Benefits

• Comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• Participation in short-term incentive programs.

Pay

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs.

Schedule

N/A

Additional Information

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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