Senior Scientist – ELISA / LBA / Biomarker

This is a fully onsite role based at our customer’s site in Boston, MA. We welcome applicants from all locations within the US. Relocation assistance is not provided. Must be legally authorized to work in the United States without sponsorship and able to pass a comprehensive background check, including a drug screening.

About the role

Join Thermo Fisher Scientific’s clinical research business, a leading global contract research organization and world leader in serving science. Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by embedding sustained groups of talent within our customers’ organizations to provide long-term support. This collaborative approach enhances capabilities and advances the delivery of life-changing therapies.

Responsibilities

• Prior hands-on experience developing ligand binding assays for translational or clinical applications.
• Experience developing and validating assays, with working knowledge of assay validation expectations and fit-for-purpose principles.
• Design and execute method development activities for innovative biomarker assays intended for use as primary, secondary, or exploratory endpoints in clinical trials.
• Evaluate assay feasibility and strategies for the measurement of novel biomarkers in relevant biological matrices, including human biofluids and tissues.
• Collaborate with senior members of the Biomarkers group and cross-functional partners to develop, optimize, and implement high-quality biomarker assays.
• Apply knowledge of biomarkers, translational medicine, and assay validation principles to design robust assays suitable for clinical trial use and aligned with regulatory expectations, including FDA requirements.
• Perform mock validation experiments and contribute to generation of data packages supporting assay readiness.
• Support assay transfer activities to CROs and external laboratories, including technical handoff and troubleshooting as needed.
• Analyze, interpret, and clearly communicate experimental results to internal stakeholders and project teams.
• Present data at team and project meetings as needed.

Requirements

• Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar.
• Sr. Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years) OR Masters degree and previous experience (comparable to 2+ years) OR PhD.
• In some cases, an equivalency consisting of a combination of appropriate education, training, and/or directly related experience will be considered sufficient.
• Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
• Able to work upright and stationary and/or standing for typical working hours.
• Able to lift and move objects up to 25 pounds.
• Able to work in non-traditional work environments.
• Able to use and learn standard office equipment and technology with proficiency.
• May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Skills

• Method development and validation experience (Ligand binding assays, Immunoassays, ELISA).
• Biomarker Assay optimization and troubleshooting.
• Western blot.
• Protein labeling and quantification.
• Molecular biology techniques.
• Cell biology techniques.
• Data interpretation and presentation.

Schedule

• Full-Time; Monday – Friday; 8am-5pm EST.

Benefits

• Competitive remuneration and annual incentive plan bonus.
• Healthcare benefits, including medical, dental, and vision plans.
• Employee assistance and family support programs, including commuter benefits and tuition reimbursement.
• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave).
• Accident and life insurance, and short- and long-term disability.
• Retirement and savings programs, including a competitive 401(k) U.S. retirement savings plan.
• Employees’ Stock Purchase Plan (ESPP) offering the opportunity to purchase company stock at a discount.

Pay

The salary range estimated for this position based in Massachusetts is $95,000.00–$105,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy.