Senior Associate Scientist - Bioanalytical & Biomarker Technologies

About the role

We are seeking a dynamic senior associate scientist to join our bioanalytical & biomarker technologies group. The candidate will design and execute analytical and bioanalytical methods to support biotherapeutics discovery and preclinical development.

Responsibilities

• Design, execute, and troubleshoot LC-MS and HPLC methods for analytical characterization of bioconjugates and bioanalytical quantification of therapeutics.
• Support a range of modalities including monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs), siRNA/oligonucleotides, and endogenous biomarkers across diverse biological matrices.
• Perform end-to-end sample preparation (e.g., LLE, SPE, affinity capture, enzymatic digestion, homogenization) and operate LC-MS/MS workflows from instrument setup to data analysis.
• Analyze and interpret results; summarize findings, propose next steps, and present data at internal meetings.
• Document experiments, methods, and results in electronic lab notebooks (ELNs) with clarity and rigor; contribute to SOPs and method documentation.
• Maintain instruments and general lab readiness; troubleshoot systems and ensure data integrity and instrument uptime.
• Evaluate and implement new platforms, workflows, and automation to improve throughput, sensitivity, and robustness.
• Prioritize effectively across multiple projects and timelines, collaborating closely with colleagues in discovery biology, DMPK/PK-PD, and process/analytical teams.

Requirements

• BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Science or a related discipline with 3+ years hand-on experience.
• Experience in liquid chromatography and/or mass spectrometry is preferred, with the ability to execute, qualify, and optimize analytical methods.
• Hands-on experience in sample preparation techniques (LLE, SPE, affinity capture, enzymatic digestion, homogenization, etc.)
• Experience with automation platforms is a plus.
• Detail-oriented, good interpersonal and effective technical communication skills (written and verbal).
• Ability to manage multiple projects in a fast-paced environment.
• Collaborative team player with a growth mindset to quickly adapt to evolving priorities and continuously learn to embrace new challenges.
• Previous exposure in bioanalysis of LC-MS based small molecule, oligonucleotides, biomarkers and biotherapeutics assay development is beneficial.

Qualifications

• BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Science or a related discipline.
• 3+ years of hands-on experience in liquid chromatography and/or mass spectrometry.
• Experience in sample preparation techniques (LLE, SPE, affinity capture, enzymatic digestion, homogenization, etc.).
• Experience with automation platforms.
• Detail-oriented, good interpersonal and effective technical communication skills (written and verbal).
• Ability to manage multiple projects in a fast-paced environment.
• Collaborative team player with a growth mindset to quickly adapt to evolving priorities and continuously learn to embrace new challenges.
• Previous exposure in bioanalysis of LC-MS based small molecule, oligonucleotides, biomarkers and biotherapeutics assay development.

Skills

• Experience in liquid chromatography and/or mass spectrometry.
• Hands-on experience in sample preparation techniques.
• Automation platform experience.
• Detail-oriented and strong interpersonal skills.
• Ability to prioritize and manage multiple projects.
• Collaborative team player with a growth mindset.
• Experience in bioanalysis of LC-MS based small molecule, oligonucleotides, biomarkers and biotherapeutics assay development.

Benefits

• Annual bonuses or other incentive plans.
• Equity awards.
• Pension or retirement benefits.
• 401(k) company match.
• Health and wellness programs.
• Fitness centers.
• Insurance benefits (e.g. medical, dental, vision, life and disability).
• Paid time off.
• Family support benefits.

Pay

$80,300.00 - $131,100.00 annually

Schedule

Full-time