Senior Scientist, Biologics Cell Line Development

About the role

The Senior Scientist will lead CHO-based cell line development for biologic therapeutics moving into clinical development. They will innovate through the development of improved genetic components, host cell line engineering, and process optimization. They will also represent the team on cross-functional projects and contribute to industry conferences, patent filings, and peer-reviewed publications.

Responsibilities

• Perform CHO cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment.
• Drive innovation through the development of improved genetic components, host cell line engineering, and cell line development process optimization.
• Identify emerging practices for biologics cell line development and manufacturing to shape scientific strategies and continued innovation.
• Represent the cell line development team on cross-functional projects, making decisions for cell line activities and effectively communicating results, progress, and plans.
• Represent Asimov externally, contributing to industry conferences, industry forums, filing patents, and publishing peer-reviewed manuscripts.
• Manage and mentor a team of 3+ scientists focused on CHO-based biologics CLD, providing technical direction and supporting them in their professional development.

Requirements

• Experience of 5+ years CHO-based cell line development, stemming from expressing IgGs and bispecifics in an industrial CLD environment.
• A Ph.D. in Biological Engineering, Cell Biology, Molecular Biology, or a related field.
• Minimum 1 year experience managing direct reports and providing technical guidance.

Qualifications

• Experience working with a global customer base is a plus, but not required.

Skills

• Experience with vector optimization to improve titer and product quality attributes for complex bispecific scaffolds.
• Experience with CLD process optimization.
• Experience with development of automated high-throughput screening for CLD workflows.

Benefits

Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

Pay

$145K - $165K

Schedule

N/A