Senior Scientist, Biochemical and Cellular Pharmacology
About the role
The successful candidate will be part of a dynamic, highly collaborative team driving the discovery and characterization of innovative therapeutic drug candidates that could transform patient outcomes. Operating at the intersection of cutting-edge science and drug development, you will play a crucial role in selecting and evaluating different modalities of therapeutic candidates from early-stage research to final IND candidate selection. In this role, you will apply your deep expertise in G-protein coupled receptor (GPCR) pharmacology to establish screening assay cascades and dissect complex receptor mechanisms of action to inform target candidate profiles. You will lead and contribute to the development, optimization, and execution of sophisticated molecular pharmacology assays, acting as a primary subject matter expert on project teams and shaping program directions.
Responsibilities
- Serve as the primary GPCR expert and strategic advocate for Biochemical and Cellular Pharmacology on multidisciplinary project teams, contributing both at the bench and at leadership levels to drive decision-making.
- Oversee and contribute to rigorous in vitro pharmacological characterization to advance lead candidates in the cardiovascular, renal, or metabolic disease fields.
- Lead the development, optimization, and execution of advanced molecular pharmacology assays—focusing heavily on protein-protein interactions, secondary messengers, and biosensors—to interrogate complex GPCR mechanisms of action in transfected and primary cells.
- Work within multidisciplinary teams and provide direct scientific mentorship and strategic guidance to Scientist partners to execute complex experiments, streamline workflows, and ensure robust data analysis.
- Demonstrate scientific curiosity by maintaining deep domain expertise and continually evaluating, adopting, and leveraging rapidly advancing technologies to evolve our pharmacological capabilities and