Senior Principal Scientist - Bioanalytical Sciences

About the role

The Assay Development Group (ADG) in Bioanalytical Sciences, located in Tarrytown, NY, is seeking a Senior Principal Scientist.

Responsibilities

• Create and execute novel assay strategies for all biotherapeutic modalities, designing experiments, troubleshooting problems, organizing and interpreting experimental results and performing follow-up experiments.
• Supervise a team of scientists in the development and validation of immunoassays for the measurement of drug, drug complexes and antidrug antibodies to support new programs.
• Guide the designs and execution of immunoassays (PK, PD and ADA) by direct reports, based on protocols provided by literature, seminars and other scientists. Suggest troubleshooting experiments for assay-related problems, follow-up experiments to further assay development and optimize assays.
• Routinely reviews data for multiple developmental projects, working on these projects simultaneously. Summarizes and presents results internally to management and externally in industry meetings.
• Writes/reviews assay validation protocols, reports and SOPs prior to submission to Quality Auditing (QA).
• Functions as Study Director for assay validation studies conducted by direct reports.

Requirements

A PhD degree with 5+ years or a MS with 8+ years or a BS with 10+ years meaningful experience is required. An in-depth understanding of the science and technology on the development and validation of immunoassays is required. The ability to perform sophisticated technical tasks to pursue projects that incorporate a diverse set of skills and work on multiple projects/experiments simultaneously is helpful.