Senior Principal Scientist, Bioanalytical

Senior Research Scientist- Onsite, Lenexa, KS- Full-Time; Flow Cytometry ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development. We are excited to be seeking a new Senior Principal Scientist at ICON in Lenexa, Kansas (KS). The Senior Principal Scientist will lead and conduct scientific research aimed at advancing clinical trials and developing innovative therapies. You will manage sponsor programs, shape assay strategies, and provide expertise for new and complex modalities. We are seeking candidates with proven method development and Spectral Flow Cytometry experience. What You Will Do The Senior Principal Scientist is responsible for method development and validation for testing preclinical and clinical specimens using flow cytometry, and ligand-binding analytical methods. In addition, you will oversee transfer robust flow cytometry methods for further for bioanalytical testing. Desired Experience (flow cytometry experience required, ligand binding experience preferred): Flow cytometry Experience with Spectral FlowPanel designGating strategy designUsage of cytometry software (e.g. FACSDiva, FCS express) Ligand binding assaysELISA, ECLIA PK, PD, and immunogenicityUsage of relevant software (e.g. SoftMax Pro, Watson) Method Development Designs and executes experiments for method developmentDevelops new scientific approaches to method development and communicates these to the global science teamMentors junior scientists and advises operation on developed methodsReviews and approves data of other scientistsCommunicates with team members and management regarding project status, purpose, scheduling, problems, etc.Lead communication with clients regarding project status. Scientific Maintain knowledge and skill in all techniques where you perform your work.Provide scientific input to management and BD about new technology investments and lines of service.Own discussions regarding scientific results with sponsors, together with project managerPromotes ICON utilizing scientific skills through scientific communication such as external publication of posters and journal articles.Perform R&D projectsTraining of technicians on technical aspectsMentor and train staff on scientific topics Quality and Timely Work Execution Takes initiative in process development and SOP/WI writingLegible, logical and reproducible documentation of all experimentationHas a thorough understanding and complies with GLP and other appropriate regulationsDevelops rugged and economical assaysPerforms data review of other scientist’s work Sample Analysis and Assay Validation Provides key assay input to the validation and bioanalysis team(s) to ensure successful executionAssay troubleshootingMay perform and document maintenance, trouble-shooting and repairs on advanced instrumentation with support of service engineers or other trained supervisory personnel. Qualifications Read, write and speak fluent EnglishSpectral flow cytometry experience10-15 years of relevant laboratory experienceMS or PhD with applicable research in a relevant scientific field, preferredPresenter/Publisher in Regulated relevant field, preferred What ICON Can Offer You Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family. Our Benefits Examples Include Various annual leave entitlements A range of health insurance offerings to suit you and your family’s needs. Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being. Life assurance Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others. Visit our careers site to read more about the benefits ICON offers. At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles. Are you a current ICON Employee? Please click here to apply