Senior Director, Market Transformation

Key Responsibilities

• Monitor the external healthcare, market, and policy landscape to identify trends, risks, and opportunities relevant to Vertex brands and access strategies
• Provide actionable market insights that enable cross-functional teams to make informed brand, access, and commercialization decisions
• Support key product launches and portfolio optimization efforts by identifying market transformation opportunities that drive sustainable growth
• Evaluate and advance new solutions in areas such as AI, digital health, and alternative distribution models (e.g., CDS, telehealth)
• Design, develop, and activate innovative programs that drive awareness for our brands and improve patient access (e.g., develop business care, scout/select solutions, gain approval of programs)
• Rigorously evaluate the business value of proposed opportunities and capabilities using defined criteria, prioritizing programs with the most potential
• Establish and monitor adoption metrics and key KPIs, providing regular reporting to BU leadership on utilization and value realization
• Continuously assess operational efficiencies and innovative approaches that improve execution and patient outcomes
• Scale programs that demonstrate measurable impact and are ready for broader implementation across teams and partners
• Partner closely with Commercial, Market Access, Medical, Patient Support, Legal, Compliance, and other key functions to ensure alignment and execution
• Identify and cultivate relationships with new and influential external stakeholders, organizations, and partners to expand reach and enhance patient impact
• Lead with a strategic, patient-centered mindset while ensuring programs align with Vertex goals, standards, and compliance requirements
• Act as the primary liaison on BULT for market transformation, translating business needs into clear, prioritized opportunities and owning program execution within the BU

Qualifications

• Bachelor’s degree required; advanced degree preferred
• 12+ years of educational/work experience in biopharmaceuticals, healthcare strategy, commercial innovation, market access, consulting, or a related field
• Significant proven ability to translate external market insights into strategic recommendations and business action
• Experience developing and implementing innovative healthcare solutions, partnerships, or patient access programs
• Strong understanding of the healthcare ecosystem, including market dynamics, access considerations, and stakeholder engagement
• Demonstrated success leading complex, cross-functional initiatives in a highly matrixed environment
• Strong executive presence, communication, and influence skills
• Ability to identify opportunities early, solve problems creatively, and drive execution with measurable impact