Senior Clinical Informatics Analyst

About the Role

PANTHERx is the nation’s largest rare disease pharmacy, dedicated to providing uncompromising quality and superior health outcomes for patients living with rare and devastating diseases. We are seeking inspired, compassionate problem solvers who thrive in a dynamic healthcare environment and are committed to achieving the highest quality outcomes for our patients.

At PANTHERx, employees are the driving force behind our mission. We cultivate talent, encourage growth, and support career exploration within the organization. This role bridges clinical operations and IT delivery, translating clinical workflows and business needs into structured, testable requirements while ensuring system configurations reflect the realities of clinical practice.

Responsibilities

• Clinical Analysis & Requirements
  • Analyze clinical workflows, operational processes, and business needs to develop structured technology requirements, including user stories and acceptance criteria that meet Informatics methodology standards.
  • Conduct current-state and future-state workflow analysis for clinical systems, identifying gaps, risks, and design considerations before work enters delivery.
  • Document clinical requirements with precision to enable QA to execute acceptance criteria directly, aligning with the Informatics-to-QA handoff standard.
• System Design & Integration Support
  • Provide clinical informatics input on system configuration, integration design, and data flow decisions to ensure solutions align with clinical workflow requirements and data standards.
  • Evaluate interoperability requirements for clinical systems, applying knowledge of NCPDP, HL7, and FHIR standards to ensure integration designs are clinically sound and technically executable.
  • Participate in technical design reviews, contributing clinical perspective on decisions affecting pharmacy operations, patient care workflows, or clinical data integrity.
• Documentation & Standards
  • Produce high-quality requirements documentation, workflow diagrams, and business process models that meet Clinical Informatics methodology standards.
  • Maintain and update clinical system documentation, including integration specifications, configuration guides, and workflow maps as systems evolve.
  • Contribute to the development and refinement of Clinical Informatics standards, templates, and quality benchmarks in collaboration with the Sr. Manager.
• Cross-Functional Collaboration
  • Partner with Business Analysts, Product Owners, and QA to ensure clinical requirements are accurate, complete, and directly usable in delivery and test execution.
  • Serve as a clinical subject matter resource for Data & Analytics, IT Infrastructure, and AI teams on projects with clinical workflow or data implications.
  • Mentor Clinical Informatics Analysts, providing guidance on clinical documentation standards, workflow analysis, and requirements quality.

Requirements

• Required Qualifications
  • 5+ years of experience in clinical informatics, pharmacy informatics, clinical operations, or a closely related field.
  • Demonstrated clinical domain knowledge, including familiarity with pharmacy operations, clinical workflows, and supporting technology systems.
  • Proven ability to document clinical requirements with precision for technology delivery and QA test execution.
  • Experience conducting workflow analysis and translating operational needs into structured technology requirements.
  • Strong written communication skills, with the ability to produce clear, precise documentation for clinical and technical audiences.
• Preferred Qualifications
  • Experience in specialty pharmacy, rare disease, or high-complexity clinical environments.
  • Familiarity with interoperability standards: NCPDP, HL7 FHIR, and pharmacy-specific data exchange formats.
  • Exposure to clinical decision support, medication management systems, or prior authorization workflows.
  • Familiarity with agile delivery practices and acceptance criteria standards to contribute directly to story-level requirements.
  • Bachelor's degree in Pharmacy, Health Informatics, Nursing, Information Systems, or a related field, or equivalent experience.

Work Environment

This position works in a hybrid home office and professional office environment. Routine use of standard office equipment such as computers, phones, photocopiers, filing cabinets, and fax machines is required. Communication is primarily via MS Teams.

Physical Demands

The role requires regular sitting, seeing, talking, or hearing. Frequent standing, walking, use of hands and fingers to handle or feel, and reaching with hands and arms are necessary. Visual acuity is required for tasks such as reading and working with data on a screen. Reasonable accommodations may be made to enable individuals with disabilities to perform essential job functions.

Benefits

• Hybrid, remote, and flexible on-site work schedules, based on the position.
• Comprehensive benefits package, including:
  • Medical, dental, and vision coverage.
  • Health savings and flexible spending accounts.
  • 401K with employer matching.
  • Employer-paid life insurance and short/long-term disability coverage.
  • Employee Assistance Program.
• Generous paid time off for all full-time employees, including paid holidays.

Location: Pittsburgh, PA (Hybrid) | Classification: Exempt | Status: Full-Time | Reports to: Senior Manager, Clinical Informatics