Senior Associate Scientist, Viral Delivery Technologies (AAV)

About the role

The Viral Delivery Technologies group is seeking a highly motivated Senior Associate Scientist to support development of an antibody-retargeted adeno-associated virus (AAV) delivery platform. This role will support the design, characterization, and in vitro/in vivo validation of novel AAVs, further expanding the company's gene therapy vector delivery portfolio.

Responsibilities

• Design, execute, analyze, and troubleshoot in vitro experiments to characterize and validate antibody-retargeted viral vector designs, screening protocols, and performance.
• Perform basic molecular biology and protein analysis techniques (e.g., cloning, SDS-PAGE, Western blotting, ELISA, DNA extraction, PCR, qPCR, protein chromatography).
• Partner with the bioinformatics team to translate vector designs into screening platforms.
• Execute rAAV production protocols and expand our understanding of AAV biology to inform novel vector optimizations.
• Collaborate with cross-functional team members, collaborators in analytical groups, and core facilities across Research and Discovery.
• Participate in team meetings and prepare regular updates and presentations for departmental forums.

Requirements

• At least a B.A./B.S. degree with 5+ years of relevant industry or academic experience.
• An M.S. in cell biology, molecular biology, biochemistry, protein purification, and/or antibodies is preferred.
• Experience with mammalian cell culture; manipulation and purification of viruses and/or proteins; DNA isolation from tissues and cells; plasmid cloning; use of antibodies in various applications; and maintenance of accurate, up-to-date electronic lab records.
• Familiarity with key antibody properties, protein engineering, viral vector production, and relevant research software (e.g., Microsoft Office, GraphPad Prism, Benchling, MacVector).

Qualifications

• Enjoy working in an innovation-driven, highly collaborative, fast-paced environment.
• Have an affinity for bioengineering and technology-development projects.
• Be highly motivated and seek continual improvement.
• Be rigorous, have strong attention to detail, and can effectively balance multiple projects.
• Have excellent presentation and communication skills.

Benefits

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Pay

$80,300.00 - $131,100.00 annually

Schedule

Full time