Scientist I/II, Antibody Therapeutics

About the role

We are looking for a highly motivated and innovative scientist to join our biologics discovery group at GondolaBio. The selected candidate will work within a fast-paced, interactive, and innovative research team to assist in the development of novel antibodies. This role will require a highly cross-functional skillset, including cell biology, immunology, and protein engineering.

Responsibilities

• Design and perform studies critical for antibody discovery and validation, including binding assays (e.g., ELISA, flow cytometry, BLI), and functional cell-based assays, including immunological assays, internalization and cellular trafficking assays.
• Support translational studies that further elucidate the mechanism and biology for drug candidates, including potential biomarker development, in vivo model selection and efficacy evaluation.
• Identify and manage CROs to complement internal efforts.
• Analyze experimental data and present findings to the team.
• Maintain accurate and detailed laboratory records, including experimental procedures, results, and conclusions.
• Contribute to the preparation of technical reports, presentations, and scientific publications.
• Participate in project meetings and contribute to the design and planning of experiments.
• Communicate effectively with team members and external collaborators.
• Contribute to due diligence and gap analysis on potential new GondolaBio assets.

Requirements

• Ph.D. in Biochemistry, Cell Biology, Immunology or related discipline with 2+ years hands-on industry experience. M.S. and B.S. candidates with equivalent experience will also be considered.
• Experience with antibody screening and developability assays (e.g., ELISA, flow cytometry, BLI, developability assessments).
• Strong hands-on experience with setting up, and optimizing in vitro cell-based assays, including immunological assays (e.g., ADCP, ADCC, CDC), and cellular trafficking (e.g. confocal microscopy).
• Experience in designing and executing in vivo studies for efficacy and PK/PD evaluation of biologics.
• Strong problem-solving skills, attention to detail, and teamwork.
• Ability to work in a fast-paced environment.
• Strong scientific background and achievements in bioscience and translational medicine, ideally demonstrated by scientific publications, presentations, and/or patents.
• Proven track record of successfully working in research programs.
• Strong understanding of drug discovery and development processes.
• Excellent communication (written & verbal) and organizational skills.
• Ability to think strategically and execute experiments effectively.
• Experience in collaborating with cross-functional teams and external partners.
• Demonstrate creative 'out of the box' thinking to solve complex technical problems and champion innovative technologies to achieve project goals.
• Commitment, drive, and ownership mindset.

Qualifications

• Education: Ph.D. in Biochemistry, Cell Biology, Immunology or related discipline with 2+ years hands-on industry experience. M.S. and B.S. candidates with equivalent experience will also be considered.

Skills

• Experience with antibody screening and developability assays (e.g., ELISA, flow cytometry, BLI, developability assessments).
• Strong hands-on experience with setting up, and optimizing in vitro cell-based assays, including immunological assays (e.g., ADCP, ADCC, CDC), and cellular trafficking (e.g. confocal microscopy).
• Experience in designing and executing in vivo studies for efficacy and PK/PD evaluation of biologics.
• Strong problem-solving skills, attention to detail, and teamwork.
• Ability to work in a fast-paced environment.
• Strong scientific background and achievements in bioscience and translational medicine, ideally demonstrated by scientific publications, presentations, and/or patents.
• Proven track record of successfully working in research programs.
• Strong understanding of drug discovery and development processes.
• Excellent communication (written & verbal) and organizational skills.
• Ability to think strategically and execute experiments effectively.
• Experience in collaborating with cross-functional teams and external partners.
• Demonstrate creative 'out of the box' thinking to solve complex technical problems and champion innovative technologies to achieve project goals.
• Commitment, drive, and ownership mindset.

Benefits

Patient Days, where we are fortunate enough to learn more about the lives we are looking to impact and a real exchange of ideas as to how we can improve our efforts.
A culture inspired by our values: put patients first; think independently; be radically transparent; every minute counts; and let the science speak.
Collaborative business environment.
Excellent compensation package (Base, Performance Bonus, Equity).
Excellent benefits package.
Flexible PTO.
A fast-paced, data-driven, work environment with world-class R&D minds and capabilities.
Work with the most productive groups of R&D operators in the industry.
A platform for meaningful scientific contributions to shine.

Pay

The base pay range for this position is $100,000 to $140,000 per year. The actual compensation offered will be determined based on a number of job-related factors, including experience, skills, qualifications, and location. A bonus plan and equity will also be offered.