Research Fellow - Lab Medicine and Pathology

About the role

The Research Fellow position is located in Rochester, Minnesota and is part of a joint project between Dr. Maia and Dr. Harrington to define transcriptional dependencies associated with serous (p53 Aberrant) endometrial cancer. The candidate will work under their mentorship.

Responsibilities

• Cultivate mammalian cell cultures, primarily intestinal organoid/tumoroid models
• Derive and establish normal and cancer organoid lines from patient samples
• Design and conduct drug screenings and evaluate the efficacy of novel therapeutics in preclinical organoid models
• Use reporter expressing organoid models to assess cell state dynamics, in response to various compounds and drug candidates, using flow cytometry analysis
• Conduct a wide range of molecular biology techniques, such as DNA/RNA extraction, PCR, qPCR, cloning, western blotting and chromatin immunoprecipitation (ChiP)
• Interpret, present, and document experiments based on generated data to investigators
• Maintain and report accurate records of data

Qualifications

• PhD in a relevant field (e.g., cancer biology, molecular biology, genetics, or related disciplines)
• Proficiency in a wide range of molecular biology techniques, including DNA/RNA extraction, PCR, qPCR, cloning, western blotting, chromatin immunoprecipitation (ChiP) and CUT&RUN
• Proficiency in mammalian cell cultures—particularly organoids
• Proficiency in bioinformatic analysis
• Excellent organizational skills and attention to detail
• Ability to work independently as well as collaboratively in a team-oriented environment
• Effective communication and interpersonal skills

Pay

$67,282.95 - $78,711.15 / year; Education, experience and tenure may be considered along with internal equity when job offers are extended.

Schedule

Full Time

Benefits

Mayo Clinic provides competitive compensation and comprehensive benefit plans, including medical, dental, vision, pre-tax savings accounts (HSA, FSA), retirement packages, and more. Employees are also eligible for the Nurse Residency Program, which supports the transition to a professional nurse.

Exemption Status

Exempt