Research Associate I, Molecular Biology/Biochemistry

About the role

Watchmaker is inviting applications for the full-time position of Research Associate I, based in Boulder, Colorado. This position reports to a Research Scientist II and will contribute to a research program focused on the development and characterization of novel, proprietary reagents for genomics applications. The Research Associate I will execute established experimental protocols, maintain accurate laboratory records, and participate as an active member of the R&D team under the guidance of senior scientists. This role is well suited for someone eager to develop hands-on laboratory skills in a dynamic, fast-paced biotech environment. The successful candidate will gain valuable exposure to next-generation sequencing technologies, enzyme biochemistry, and commercial product workflows, with opportunities to grow as they build their scientific foundation.

Responsibilities

• Execute molecular biology experiments, including PCR, qPCR, buffer optimization and next-generation sequencing sample preparation workflows
• Accurately document all experimental procedures, observations, and results in laboratory notebooks and data management systems
• Perform routine bioinformatic analyses using established pipelines under the direction of senior scientists
• Contribute to a team responsible for launch of commercially successful enzymes and genomics products
• Participate in team meetings and contribute to group scientific discussions
• Identify and communicate observations that may support process improvement

Skills and Requirements

• BS in molecular biology, biochemistry, or a related discipline
• Experience in the following areas is highly desirable: next-generation sequencing (NGS), DNA sample preparation, PCR, qPCR and NGS data analysis
• Knowledge of DNA- and RNA-modifying enzymes is a plus
• Hands-on experience with molecular biology techniques
• Ability to follow written protocols precisely and communicate deviations clearly to supervisors
• Self-motivation and sound personal task management skills
• Careful attention to detail and commitment to accurate experimental documentation
• Strong interpersonal skills and an ability to work as an effective team member
• Familiarity with basic data analysis tools (spreadsheets, descriptive statistics)
• Experience with standard molecular biology techniques such as PCR, qPCR, vector design, and gene cloning methods
• Excellent organizational skills and outstanding attention to detail
• Good communication and personal task management skills and a high level of self-motivation

Education

BS in Molecular biology, biochemistry, or a related discipline

Pay

The base compensation for the Research Associate I role starts at $65,000 - $80,000 + bonus + equity; actual pay will be adjusted based on skills and experience.

Benefits

• Flexible Time Off
• Holidays
• Employer covers 75% of base medical plan with buy-up options
• EAP (employee assistance program)
• Employer paid dental
• Employer paid vision
• Employer paid $25,000 life/AD&D policy
• Paid parental leave
• 401(k) retirement plan with a 4% match