RESEARCH ASSISTANT II - Briney Lab

About the role

The Briney Lab is seeking a Research Assistant II to join us in the Department of Immunology and Microbiology at Scripps Research. We use a combination of advanced single cell multi-omics techniques and sophisticated computational tools to deeply explore the antibody response to emerging infectious diseases. We are looking for a highly motivated individual who will contribute to antibody discovery projects against a variety of viral targets, including Lassa, Ebola, HIV, SARS-CoV-2, influenza, astrovirus, and others. The antibodies we discover have potential use as therapeutics or as templates for rational vaccine development.

Responsibilities

• Generate single cell multi-omics sequencing libraries using the 10x Genomics Chromium platform
• Perform next-generation sequencing experiments using Illumina and Oxford Nanopore systems
• Cloning, recombinant expression, and purification of monoclonal antibodies
• Production of a variety of viral antigens used for antibody isolation and characterization
• Antibody binding assessment by ELISA, BLI, and/or SPR
• Pseudovirus-based neutralization assays
• General lab responsibilities, including maintaining inventory of commonly used reagents/supplies and routine equipment maintenance
• Present work at lab meetings and contribute to peer-reviewed publications
• Work closely with other Briney Lab members and our collaborators
• Work under minimal supervision. Independently conduct a wide variety of standard laboratory techniques/procedures while using judgement when necessary to adapt standard methods and techniques.

Requirements

• Requires a bachelor’s degree in a relevant scientific discipline or an equivalent combination of education, training and/or experience from which comparable knowledge, skill and abilities have been attained.
• Requires 3-5 years’ experience. Candidates possessing a master’s degree, 2+ years’ experience required.
• Must have substantial expertise in recombinant protein production and purification.
• Experience with antibody binding assays and pseudovirus neutralization assays is highly preferred.
• Experience with single cell techniques (specifically the 10x Genomics platform) and next-generation sequencing is preferred, but is not required.
• Python programming experience would be a plus, but is not required.

Compensation

The expected hiring range for this position is $70,304 to $77,000 per year, commensurate with experience. Consideration will be given to experience that exceeds the listed requirements.

Benefits

• Comprehensive Benefits Include Employer Contributed Retirement Plan – Depending on eligibility, employees receive an employer contributed retirement plan (no employee contribution required) and the option to contribute to a 403(b) (which is similar to a 401(k) using your own pre or post-tax dollars)
• Full Suite of Health and Welfare plans including three medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more
• Access to Flexible Spending Accounts (Medical/Dependent Care)
• Competitive vacation and sick leave policies
• Free, on-site parking