Proteomics Scientist
Proxima · Boston, MA · 2 days ago
Analyst$5/hrFull-time
About the role
NeoLink is Neo's bridge to the physical world: we leverage proteomics to directly assay molecular interactions at an amino-acid level of resolution, enabling a feedback loop where machine-learning models directly explore and learn from biology. As a Proteomics Scientist, you will play a critical role in building out NeoLink and advancing critical R&D workflows for data generation and internal programs.
Tasks and Responsibilities
- Design, optimize and execute the structural and chemical proteomic workflows (cross-linking, affinity purification, proximity biotinylation, ligandability profiling) that form the core of NeoLink
- Partner with computational biologists and machine learning scientists to design experiments that produce high-quality, analysis-ready data
- Maintain, operate, and coordinate the usage of LC/MS instruments
Skills
- Excellent sample preparation skills for mass spectrometry-based proteomics
- Experience in structural proteomics (cross-linking, covalent footprinting) or chemical proteomics (activity/affinity-based protein profiling, affinity selection)
- Comfort operating in a fast-paced, results-oriented environment
- Expertise in handling and maintaining LC and MS instruments, in particular Thermo Fisher Neo Vanquish LC systems and Orbitrap or Astral mass spectrometers
- Knowledge of proteomic data analysis methods and software tools
- Accuracy and reliability in documenting and presenting scientific data
- Strong communication skills and proficiency in English