Principal Scientist - ADME - Site Based, Princeton, NJ

About the role

Cyprotex US, an Evotec company, is seeking a Principal Scientist to join our team. The ideal candidate will be a passionate and curious individual with a PhD in biology, chemistry, pharmaceutical sciences, or a related field, with 5+ years of experience. They will be responsible for managing and coordinating multiple projects, leading cross-functional collaboration, and providing expert scientific support.

Responsibilities

• Be a senior point of contact within the group for operational and scientific support across all ADME assays (troubleshooting, data analysis and interpretation).
• Identify opportunities for and lead cross-functional collaboration.
• Design and perform novel ADME assays.
• Conduct in vitro ADME assays manually or using automated liquid handling system for completion in a fast-paced environment, while managing multiple projects to meet the timelines.
• Perform Bioanalytical method development and quantification using UPLC-MS/MS.
• Actively participate in scientific discussion to resolve arising issues as well as critically analyze and interpret the data to design next steps.
• Work closely with project managers and senior management to complete the assigned work in the anticipated time frame.
• Provide expert scientific support for the wider company for ADME studies.
• Keep up to date with scientific literature advances, developments, and regulatory guidelines in the area of ADME and inform the team of relevant developments.
• Provide practical scientific guidance to others, collaborating across functions to meet project goals, and regularly presenting findings.
• Promote cross functional collaboration with other Principal Scientists and to provide opportunity for team members to contribute to these collaborations.
• Provide expert scientific support for the wider company for drug metabolism studies.
• Coach, mentor and line manage other members of the team by effective use of Evotalks meetings, regular 1to1 discussions and ad hoc interactions.
• Aid team members in generating development plans and to review and provide support to team members in executing these plans.
• Aid the VP in generating succession plans for the team.
• Responsible for managing and coordinating multiple projects/activities within the group with a results-driven approach.
• Proactively take the initiative to improve group processes and make efficiency gains in assays.
• Encourage a continuous improvement culture and to manage projects to completion.
• Participate in internal and external partner meetings as and when required.
• Ensure appropriate Health and Safety procedures are always followed in the workplace.
• Participate in all mandatory training required to perform effectively in job role.
• Ensure that your personal training record is up to date and that any gaps are discussed with your supervisor.
• Actively participate in Evotalks and agree on personal targets and expectations with supervisor.

Requirements

The successful candidate must have a PhD in biology, chemistry, pharmaceutical sciences, or an equivalent combination of education, training and experience from which comparable knowledge, skills and abilities have been attained. They should possess excellent writing and verbal communication skills, very strong organization skills and attention to detail, detailed knowledge of bioanalysis within ADME/DMPK, hands-on experience of bioanalytical method development and quantification of small molecules and peptides in complex matrices, strong understanding of UPLC-MS/MS systems, troubleshooting skills in assays and instrumentation, an understanding of pharmacokinetic parameter determination and interpretation, and experience locating and applying information in the scientific literature.

Qualifications

The base pay range for this position at commencement of employment is expected to be $113,900 to $154,100. This is a salaried exempt position. Base salary offered may vary depending on the individual's skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.

Benefits

Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.

What makes us unique

Our business model
At Evotec, our goal is to pioneer the future of drug discovery and development through cutting‑edge science, data‑driven platforms and flexible partnerships. Together for medicines that matter. Read more
Our expertise
Together, we are creators and turn imaginations into cures. With Evotec, a smart idea can unfold and mature, with the help of our high expertises and cutting-edge technologies. Read more
Our team
Our collaborative and trustful work environment enables solution-oriented discussions among colleagues. We inspire each other to great aspirations and know that, together, we’ll go further. Read more

Success Profile

Cultural fit and soft skills are important factors for success. Check out the traits we’re looking for:
Curiosity
Resilient
Creative mindset
Teamplayer
Forward-thinking
Adaptable

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