Postdoctoral Fellow – RNA biology and RNA chemical modifications (Whipple Lab, Harvard University)

About the role

The Whipple Laboratory seeks a postdoctoral researcher to study the molecular functions of small nucleolar RNAs (snoRNAs), with a focus on orphan snoRNAs in neuronal systems. The successful candidate will lead projects to identify and characterize the targets and molecular mechanisms of neuronally expressed orphan snoRNAs.

Responsibilities

• Lead projects to identify and characterize the targets and molecular mechanisms of neuronally expressed orphan snoRNAs.
• Integrate transcriptome-wide mapping of RNA–RNA interactions, CRISPR-based perturbation approaches, and functional assays to define how snoRNAs engage RNA targets and regulate gene expression at the post-transcriptional level.
• Collaborate with other researchers to develop and implement cutting-edge technologies and computational methods to advance understanding of snoRNA function.

Requirements

• Recent Ph.D. in a relevant field (e.g., biochemistry, molecular biology, genetics).
• Demonstrated research productivity through peer-reviewed publications.
• Strong experimental background in RNA biology in mammalian systems.
• Experience with high-throughput sequencing techniques (e.g., CLIP-seq, RNA-seq, Ribo-seq) and familiarity with or interest in computational analysis of sequencing data.

Qualifications

• Strong written and oral communication skills.
• Interest in gene regulation, computational biology, and neurobiology.

Skills

• Expertise in RNA biology and mammalian systems.
• Familiarity with high-throughput sequencing techniques and computational analysis.
• Ability to design and execute complex experiments.
• Strong problem-solving and critical thinking skills.

Benefits

• Collaborative and interdisciplinary environment.
• Access to state-of-the-art genomics, imaging, and computational resources.
• Career development support, including fellowship applications and transition to independent positions.

Pay

The salary range for this position is $60,000 - $70,000 per year.

Schedule

The position is full-time and permanent.

Contact

To apply, please submit a CV, a brief cover letter describing previous research experience and future interests, and contact information for 2–3 references via email to amanda_whipple@fas.harvard.edu.