Postdoctoral Fellow-MSH-32074-066

Salary: $74,692 | Physical work location: 1470 Madison Ave, Hess Bldg, 7th Fl, New York, NY 10029

Principal Investigator: Cameron McAlpine, 857-207-8093, Cameron.mcalpine@mssm.edu

Lab website | Department website

Administrative Contact: Mikaela Walcott, Mikaela.walcott@mssm.edu, 212-824-8907

About the role

Research Project: Evaluate neuronal control of macrophage function in the heart. The candidate will use fundamental science tools to test how the nervous system regulates macrophage function and biology in the heart. The candidate will test how neurotransmitters and neuropeptides modify macrophage subsets and inflammatory processes in the heart and its vasculature at steady state, after myocardial infarction, during atherosclerosis, or in the context of other cardiovascular pathologies.

Goals/Outcomes: We will identify new ways by which the nervous system regulates inflammation in the cardiovascular system. Novel signaling mechanisms will be further developed and tested for therapeutic intervention.

Responsibilities

• Mouse modeling and handling
• Flow cytometry
• Advanced confocal imaging of the heart
• Single-cell sequencing
• Neuronal manipulation methods (neuronal ablation, neuropeptide deletion, brain circuit manipulation)
• Molecular assays (protein quantification, mRNA expression)

Requirements

• PhD
• 0 years of experience required

About the employer

The Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, over 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education.

Mount Sinai advances health for all people by tackling complex health care challenges through discovery, education, and patient-centered care. The system integrates hospitals, labs, and schools to deliver comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics.

The Health System includes more than 9,000 primary and specialty care physicians, 13 joint-venture outpatient surgery centers, and over 30 affiliated community health centers. Consistently ranked by U.S. News & World Report’s Best Hospitals, Mount Sinai holds high "Honor Roll" status and is ranked No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in multiple specialties including Diabetes/Endocrinology, Gastroenterology, Neurology, Orthopedics, Pulmonology, Rehabilitation, and Urology.

The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally.

Mount Sinai is committed to fostering an inclusive environment where everyone can contribute to excellence. Team members are encouraged to actively participate in creating a culture of fairness, respect, and empowerment. Leaders are dedicated to challenging outdated practices and promoting continuous learning to enhance patient care and workplace experiences.

Pay

The salary range for this role is $72,500 – $80,000 annually. Actual salaries depend on experience, education, and operational need. This range does not include bonuses, incentive pay, or other forms of compensation or benefits.