Payer Engagement Lead (National Accounts)

About the role

The Payer Engagement Lead, National Accounts, is a critical role at Praxis Precision Medicines. This individual will own and set the national payer engagement strategy, influencing coverage and reimbursement decisions for Praxis therapies. The position requires extensive experience in market access and payer engagement, with a strong focus on building trusted relationships and driving patient access.

Responsibilities

• Own and set the enterprise payer engagement strategy for national health plans, PBMs, GPOs, and other enterprise payer organizations.
• Build trusted relationships with senior payer executives responsible for formulary strategy, reimbursement, utilization management, and coverage policy.
• Communicate the clinical, economic, and value proposition of Praxis therapies to support favorable coverage and reimbursement decisions.
• Lead Medicare Part D engagement strategies, leveraging established relationships with plan sponsors and PBM leaders to support payer readiness, formulary review, and successful product launches.
• Serve as the principal decision-maker on the payer strategy inputs to commercial strategy, pricing, evidence generation, contracting, forecasting, and lifecycle planning.
• Partner closely with Medical Affairs, Commercial, Market Access, Finance, Legal, and Executive Leadership to ensure payer strategies are aligned with broader business objectives.
• Anticipate shifts in the payer environment, identifying emerging risks and opportunities that could impact patient access and commercial success.
• Represent Praxis externally as a recognized thought leader and spokesperson within the national payer community.

Qualifications

• Bachelor's degree required; advanced degree in business, healthcare, life sciences, or a related discipline preferred, or equivalent experience.
• Extensive experience (typically 15 or more years) leading national payer engagement, market access, national accounts, or related commercial functions within the pharmaceutical or biotechnology industry, with a track record of setting strategy at the enterprise level rather than executing it.
• Demonstrated success influencing access and reimbursement decisions with national health plans, PBMs, GPOs, and other enterprise payer organizations.
• Recognized authority on U.S. market access, including commercial plans, Medicare Part D, specialty pharmacy, reimbursement, and evolving payer dynamics.
• Experience developing and executing Medicare Part D account strategies and engaging senior decision-makers responsible for formulary placement, utilization management, and reimbursement policy.
• Experience owning payer strategy through product launches, including payer strategy, account planning, value communication, and cross-functional commercialization.
• Experience in CNS, specialty pharmaceuticals, rare disease, or other complex therapeutic areas strongly preferred.
• Strong business acumen with the ability to connect market dynamics to commercial performance and patient access.
• A high degree of ownership, intellectual curiosity, sound judgment, accountability, and the latitude to set objectives independently.
• Ability to travel approximately 50–70% based on business needs.

Benefits

Praxis offers an annualized base salary range of $225,000 USD - $245,000 USD, along with comprehensive benefits including medical, dental, vision, retirement plans, and paid time off.