Manufacturing Science and Technology (MSAT) Applications Administrator

About the role

This position is on-site at our Holly Springs, North Carolina facility.

Responsibilities

• Platform ownership and reliability
• Administer and support SIMCA-online, Statistica Server, and PAT platforms
• Manage Windows Server services, capacity, and uptime; tune performance and troubleshoot latency
• Maintain SQL Server/Oracle databases for configurations, results storage, and audit trails
• Integrate with DCS/SCADA (e.g., DeltaV), historians (e.g., OSIsoft PI/AVEVA), MES (e.g., Syncade), LIMS/ELN, and OPC UA/DA/MQTT gateways
• Manage data retention, archival, and restoration aligned to corporate data governance
• Ensure cGxP compliance, data integrity (ALCOA+), and security across integrations
• Partner with QA/CSV on risk-based validation (GAMP 5, CSA) and audit readiness
• Security and access management
• Implement RBAC/least-privilege, AD/LDAP integration, and SSO where applicable
• Manage audit trails, e-signatures, certificates, vulnerability management, and patching within validated-state controls
• Operations and continuous improvement
• Lead incident/problem/change management; conduct root cause analysis and drive CAPAs
• Monitor connectors, job queues, and data flows; plan upgrades, patch cycles, and license/vendor management
• Implement and test backup/restore, business continuity, and disaster recovery
• Audit and inspection readiness
• Maintain complete and contemporaneous records of configurations, changes, and deviations
• Support internal/external audits and health authority inspections

Requirements

• Bachelor’s degree in Computer Science, Engineering, Scientific field, or equivalent practical experience
• 5+ years in MSAT systems administration or historian applications including SIMCA-online, TIBCO Statistica, synTQ, AspenTech, and/or historian platforms
• Strong Windows Server and Active Directory administration; PowerShell scripting; SQL Server/Oracle fundamentals
• Experience with OSIsoft PI/AVEVA, OPC UA/DA, DCS/SCADA, MES, LIMS/ELN, and API/file-based integrations
• Practical knowledge of cGxP, data integrity (ALCOA+), Computer Systems Validation (CSV), GAMP 5, and CSA approaches
• Familiarity with ITIL-based change/incident/problem management and service operations

Qualifications

• Nice to have: Background in biopharma manufacturing or process development environments
• Experience designing secure architectures with SSO, certificates, and electronic signatures in validated systems
• Performance tuning, capacity planning, and proactive monitoring for real-time analytics platforms

Skills

• Hands-on experience with MSAT systems administration

Benefits

• Comprehensive benefits package including medical, dental, vision and prescription drug coverage with the option of a Health Savings Account with company contributions
• Industry leading 401(k)savings plan
• Insurance coverage
• Employee assistance programs
• Variety of wellness incentives
• Paid vacation time, sick time, and company holidays

Pay

TBD

Schedule

On-site at Holly Springs, North Carolina