In Vivo Scientist

About the role

We are seeking a highly motivated In Vivo Scientist to contribute to discovery research. This position will focus on HIV research, including virus production, characterization, and support of HIV discovery efforts.

Responsibilities

• Lead the design, execution, optimization, and characterization of HIV production workflows, including inventory management.
• Conduct HIV discovery research using primary human cells (PBMCs, CD4⁺ T cells) and immortalized cell lines (THP‑1, Jurkat, MT‑4).
• Perform and analyze experiments utilizing multi‑parameter flow cytometry (≥2 colors), RT‑qPCR, PCR, ELISA, and MSD multiplex assays.
• Generate and characterize stable cell lines expressing proteins of interest.
• Support in vivo mouse studies, including tissue collection, processing, and ex vivo viral RNA isolation from tissues and/or blood samples.
• Analyze and interpret experimental data, communicate findings, and contribute to project strategy and execution.

Qualifications

• Ph.D. in Biomedical Sciences, Microbiology, Immunology, Virology, or a related scientific discipline (or equivalent combination of a lesser degree and industry experience).
• Demonstrated experience in HIV research and BSL‑2 laboratory operations; strong HIV publication record preferred.
• Familiarity with HIV host‑pathogen interactions.
• Expertise in viral propagation, concentration, and characterization techniques, including ultracentrifugation, viral titer determination, and neutralization assays.
• Hands‑on experience with molecular biology techniques: CRISPR gene editing, siRNA knockdown, transfection, site‑directed mutagenesis, and Western blotting.
• Experience with in vivo mouse studies, animal handling, tissue harvesting, and viral RNA isolation from ex vivo tissues or blood.
• Experience with ELISA.
• Proficiency with scientific data analysis and visualization software (FlowJo, GraphPad Prism, SnapGene or Geneious Prime).
• Strong problem‑solving skills, attention to detail, and ability to work effectively in a collaborative research environment.
• Authorization to work in the United States indefinitely without restrictions or sponsorship.

Nice to have

• Willingness to learn omics techniques such as MSD multiplex assays, Nomics, Olink, and 10X Genomics scRNA‑seq.

Schedule

Monday – Friday, 8:00 am – 5:00 pm with overtime as needed.

Candidates currently living within a commutable distance of West Point, PA are encouraged to apply.

Benefits

• Comprehensive medical, dental, and vision coverage.
• Life and disability insurance.
• 401(k) with company match.
• Paid vacation and holidays.
• Full‑time benefits package.