Executive Director, Program Management Office (PMO)

About the role

The Executive Director, Program Management Office (PMO) at Veracyte is responsible for transforming Veracyte’s Product Development Process (PDP) into a scalable operating model. This role will lead enterprise portfolio governance, facilitate executive updates, and standardize program cadence, templates, dashboards, decision records, timelines, risk tracking, and action management.

Responsibilities

• Transform Veracyte’s Product Development Process (PDP) into a scalable operating model for advancing initiatives from concept through launch.
• Lead enterprise portfolio governance, including intake, prioritization, stage gates, sequencing, escalations, and executive trade-off decisions.
• Facilitate monthly executive updates that create shared visibility, thoughtful decisions, and timely resolution of risks, dependencies, and blockers.
• Own annual program intake process and portfolio alignment accounting for budget, capacity, business value, and strategic fit.
• Standardize program cadence, templates, dashboards, decision records, timelines, risk tracking, and action management.
• Strengthen timeline reliability, milestone integrity, critical-path focus, and launch excellence.
• Define portfolio KPIs for velocity, operational readiness, resource use, and value realization.
• Serve as a trusted partner across Product, R&D, Operations, Bioinformatics, Software, Finance, Quality, Regulatory, Legal, Commercial, and Market Access.
• Prepare clear executive and Board communications, including decision briefs, portfolio updates, risk summaries, and program investment landscape.
• Build and lead a high-performing PMO team including hiring, career development, best practices, and a clear vision for the function.

Requirements

This is a highly visible, high-impact role for a collaborative and trusted leader who can build a next-generation Product Development Process (PDP) that brings rigor, speed, accountability, and clear decision-making to our most important work while reflecting Veracyte’s values of innovation, collaboration, and making it happen.

Qualifications

• Executive-level PMO, product portfolio management (PPM), or product governance leadership in complex, regulated environments.
• Deep expertise in product development, stage-gate governance, portfolio prioritization, resource planning, risk management, and launch readiness.
• Proven ability to transform fragmented practices into standardized, scalable, data-driven execution systems.
• Strong business acumen, with the ability to connect investment, resources, capacity, trade-offs, and ROI.
• Exceptional executive communication skills for senior leadership and development teams alike.
• Independent judgment and influence to surface risks, resolve blockers, clarify decisions, and help teams move forward.
• Strategic thinker who can design operating models while diving into details and solving problems when execution requires it.
• Passion for building a PMO center of excellence through coaching, upskilling, practical standards, and shared best practices.
• Urgency balanced with quality, collaboration, and patient impact, using agile product development methods to improve speed and transparency.
• A personable leadership style grounded in clarity, coaching, accountability, humility, and trust.

Preferred Qualifications

• 13+ years in program management, portfolio management, product development, or related leadership roles, including 8+ years leading teams or enterprise programs.
• Bachelor’s degree in life sciences, engineering, business, or related field required; advanced degree, MBA, or program/portfolio certification preferred.
• Experience in diagnostics, life sciences, medtech, biotech, pharmaceutical, or other regulated product environments.
• Balancing clinical, regulatory, quality, laboratory, tech, and commercial launch dependencies.
• Experience integrating PDP, quality management system (QMS), software development lifecycle (SDLC), and portfolio-management tools.
• Experience with portfolio analytics, scenario planning, capacity modeling, and value-based prioritization.
• Experience implementing enterprise project tools, dashboards, and reporting systems as a reliable source of truth.
• Change-management experience rolling out new ways of working.
• Aptitude with modern AI tools to automate routine work, improve reporting, and increase PMO productivity.

What We Can Offer You

• Competitive compensation and benefits.
• Commitment to fostering an inclusive workforce, where diverse backgrounds are represented, engaged, and empowered to drive innovative ideas and decisions.
• Opportunities for career growth and development.
• Recognition of your contributions through a total package that includes base pay, discretionary bonuses/incentives, and restricted stock units.

About Veracyte

Veracyte (Nasdaq: VCYT) is a global diagnostics company whose vision is to transform cancer care for patients all over the world. We empower clinicians with the high-value insights they need to guide and assure patients at pivotal moments in the race to diagnose and treat cancer. Our Veracyte Diagnostics Platform delivers high-performing cancer tests that are fueled by broad genomic and clinical data, deep bioinformatic and AI capabilities, and a powerful evidence-generation engine, which ultimately drives durable reimbursement and guideline inclusion for our tests, along with new insights to support continued innovation and pipeline development.

Pay Range

$264,000—$293,000 USD