Jobs · Information Technology · California

Director, IT Infrastructure

Arrowhead Pharmaceuticals · San Diego, CA · 6 days ago
On-siteInformation Technology$190k/yrFull-time

Responsibilities

  • Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
  • Lead, mentor, and develop a high-performing infrastructure team across multiple sites.
  • Partner with the IS leadership and business stakeholders to align infrastructure investments with organizational priorities and compliance requirements.
  • Establish and manage infrastructure budgets, vendor contracts, and technology refresh cycles.
  • Develop and communicate infrastructure KPIs, SLAs, and operational metrics to IS leadership.
  • Oversee the design, deployment, and lifecycle management of virtualization infrastructure across all company locations.
  • Manage a Microsoft Active Directory environment.
  • Drive hybrid cloud strategy and operations across Azure and AWS, optimizing workload placement, cost, and performance.
  • Ensure high availability, disaster recovery, and business continuity capabilities for all critical infrastructure components.
  • Oversee network infrastructure including LAN/WAN and SD-WAN connectivity across all company sites and cloud tenants.
  • Oversee server patching and configuration management standards across the enterprise.
  • Lead capacity planning and performance monitoring to ensure infrastructure scalability in support of business growth.
  • Maintain and test disaster recovery and incident response plans in partnership with IS and business teams.
  • Lead infrastructure-related projects from inception through delivery, including consolidations, cloud migrations, and site expansions.
  • Manage relationships with key technology vendors and MSPs, negotiating contracts and ensuring service delivery accountability.
  • Evaluate and recommend emerging technologies that drive operational efficiency and cost reduction.

Requirements

  • Bachelor's degree in Computer Science, Information Systems, Information Technology, or a related field.
  • 10+ years of progressive IT infrastructure experience, with at least 4 years in a senior leadership or director-level role.
  • Deep hands-on expertise with virtualization platforms (VMware, Nutanix, Hyper-V).
  • Demonstrated experience managing Microsoft Active Directory.
  • Strong working knowledge of AWS and Azure — architecture, operations, cost management, and security.
  • Experience managing multi-site enterprise IT environments in a regulated industry.
  • Proven track record of building, leading, and developing high-performing infrastructure teams.
  • Strong understanding of network architecture, security principles, and ITIL-based service management frameworks.
  • Experience with infrastructure compliance frameworks relevant to pharma/biotech (GxP, SOX, HIPAA).

Preferred

  • Current or previous industry certifications such as VMware VCP/VCAP, Azure Administrator/Architect, AWS Solutions Architect, or ITIL v4.
  • Experience with infrastructure-as-code tools such as Terraform, Ansible, or Bicep.
  • Experience supporting laboratory and manufacturing IT environments (OT/IT convergence) within a pharmaceutical or life sciences setting.
  • Strategic thinking and the ability to translate business needs into scalable infrastructure solutions.
  • Strong communication skills - able to present complex technical topics clearly to non-technical audiences.
  • Exceptional organizational and prioritization skills in a fast-paced, regulated environment.
  • Collaborative leadership style with a strong emphasis on team development and cross-functional partnership.
  • Data-driven decision-making and a continuous improvement mindset.

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