Director, Clinical Science and Biopharma Products

About the role

The Director of Clinical Science and Biopharma Products at Guardant Health is a leadership role within the Product team, reporting to our Senior Director of Product Management. This position is ideal for a leader with strong experience in clinical science and biopharma diagnostics product development.

Responsibilities

• Portfolio partnership: Provide clinical science leadership across all diagnostics products, collaborate with oncology portfolio product directors to incorporate biopharma requirements into product strategy, prioritization, and roadmap planning across monitoring and treatment selection products.
• Clinical workflow integration: Ensure products across the Guardant portfolio fit real-world oncology practice and operational workflows to support adoption and consistent use.
• Biopharma collaboration: Partner with biopharma stakeholders to align diagnostic and RUO/IUO solutions with biomarker-driven trials, translational research objectives, and precision medicine programs.
• RUO/IUO product support: Drive strategy and execution for RUO/IUO offerings, ensuring scientific relevance, usability for research settings, and alignment with evolving biopharma needs.
• Executive Presence: Lead strategic discussions with senior diagnostic and Biopharma stakeholders and oncologists/healthcare providers.
• Product lifecycle leadership: Lead end-to-end execution from concept through development, launch, and lifecycle expansion in partnership with cross-functional teams.
• Commercial readiness: Support launch planning, sales enablement, and field training with clear messaging and differentiated value propositions for biopharma and healthcare stakeholders.
• Cross-functional collaboration: Work closely with R&D, regulatory, medical/scientific affairs, and commercial teams to deliver strategic goals.
• Competitive intelligence: Monitor diagnostic, RUO/IUO, and research trends, regulatory developments, and competitor activity to inform differentiation and planning.
• External engagement: Represent Guardant with researchers, oncologists, healthcare systems, payers, and biopharma partners to identify unmet needs and refine strategy.
• Scientific leadership: Contribute to scientific communications and conference support to reinforce Guardant’s leadership in oncology diagnostics and research solutions.
• Accountability: Biopharma portfolio performance, adoption, strategic partnerships, and shaping long-term biopharma investment priorities in collaboration with executive leadership.

Qualifications

• Education: Typically requires a Bachelor’s degree and 15 years of related experience or 12 years with a Master’s degree, 8 years with a PhD, or 5 years and a PharmD/MD.
• Experience: 8+ years in clinical science, medical affairs, diagnostics, product management, product strategy, or commercialization in oncology diagnostics, precision medicine, or health technology, including prior biopharma experience.
• Demonstrated experience with clinical science and knowledge of clinical practice.

Skills

• Strong grounding in molecular oncology, biomarkers, and translational research, with the ability to engage credibly with scientific and research stakeholders.
• Strong understanding of molecular diagnostics, clinical science, and precision medicine applications.
• Demonstrated success launching and scaling diagnostics or research products.
• Strategic thinker with strong execution rigor, cross-functional influence, and ability to align scientific, product, and commercial teams.
• Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements.

Benefits

Guardant Health offers a comprehensive benefits package that includes:

• Health insurance
• Vision and dental coverage
• Flexible spending accounts
• Retirement savings plans
• Employee assistance programs
• Generous paid time off

Pay

The annualized base salary ranges for the primary location and any additional locations are listed below.

• Primary Location: Palo Alto, CA - $206,400 - $283,800
• Other US Location(s): $175,440 - $241,230
• If the role is performed in Colorado, the pay range for this job is: $185,760 - $255,420

Schedule

This role is available on a hybrid work model. Employees may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.