Biologist

Position Details

Client: Pharmaceutical Company
Position Title: Biologist III
Duration: 06 months (Possible extension)
Location: Worcester, MA 01605
Pay Rate: $45/hr to $50/hr

Top Skills

• Human organoid culture and co-culture models such as transwells
• Handling human tissues and processing
• BS degree in cell or molecular biology
• Experience with molecular and cellular analysis techniques including qPCR, MSD, ELISA, flow cytometry
• 4 + years experience in industry

Responsibilities

• Culture, passage, and plate human intestinal organoids to support the group's research objectives.
• Perform assays in primary 3D cell culture models such as Transwells or MPS/CIVM platforms.
• Test biologic and small molecule compounds in cell-based assays for functional readouts, including cell proliferation, cytokine release, and gene expression.
• Execute advanced molecular and cellular biology techniques, including but not limited to flow cytometry (FACS), ELISA, MSD, and qPCR.
• Process human tissue ex vivo and isolate organoids, fibroblasts, and immune cells from human tissue or blood.
• Work independently on the design, execution, and interpretation of experimental results to validate project-relevant hypotheses.
• Maintain close communication with multiple teams to support human intestinal organoid cell needs.
• Implement and innovate new experimental protocols and techniques as needed.
• Analyze, interpret, document, and report data consistently, concisely, and rigorously, both to individual stakeholders and in group settings.
• Drive project impact primarily through hands-on, lab-based activities.

Qualifications and requirements

• Bachelor's degree in Biological Sciences or a related field, with 4+ years of experience in an industry setting
• In vitro cell culture experience, including sterile techniques and handling of challenging cell types
• Comfortable handling with ex vivo human tissue and processing
• Experience with 3D cell culture models such as transwells or MPS/CIVM platforms
• Proficiency in ELISA, MSD or Luminex
• Ability to learn new skills and apply them in a fast-paced research environment
• Excellent oral and written communication skills with a collaborative mindset
• Comfortable managing, shifting timelines and evolving work priorities
• Strong creativity, problem-solving skills, and attention to detail

Skills that are a plus

• Experience with cell-based assay development
• Proficiency in multi-color flow cytometry
• Experience with gene expression analysis by qPCR
• Experience working with fibroblasts and immune cells, including T cells, B cells, and monocytes

Benefits

• Medical insurance
• Dental insurance
• Vision insurance
• 401(k) retirement plan
• Life insurance
• Long-term disability insurance
• Short-term disability insurance
• Paid parking/public transportation
• (Paid time off, paid sick and safe time, hours of paid vacation time, weeks of paid parental leave, paid holidays annually)