Jobs · Analyst · Massachusetts

Associate Scientist/Senior Associate Scientist, In Vivo Pharmacology – Study Coordinator

Manifold Bio · Boston, MA · 3 wk ago
Analyst$106k–$123k/yrFull-time

Responsibilities

  • Own end-to-end study coordination across multiple concurrent in vivo programs — from animal ordering and acclimation through dosing, bleeding, necropsy, tissue collection, and downstream handoff
  • Develop and maintain detailed study plans, timelines, and execution schedules — including who does what, when, and how, with clear accountability at every step
  • Serve as the primary point of contact between scientists, VIVO team members, vivarium staff, and external CROs — ensuring alignment on study design, timelines, and deliverables
  • Contribute to study design in collaboration with program leads — including dose selection, group sizes, timepoints, route of administration, and endpoint strategy
  • Perform and oversee hands-on in vivo procedures including dosing (IV, SC, IP, PO), bleeds, perfusion, necropsy, and tissue collection as needed
  • Write, review, and refine study protocols and SOPs; contribute to protocol amendments as studies evolve
  • Track and manage animal orders, reagent inventory, and study materials to ensure readiness ahead of each experiment
  • Identify bottlenecks and resource conflicts across the study portfolio and proactively surface solutions
  • Mentor and train junior VIVO team members on in vivo techniques and study execution best practices
  • Maintain accurate, organized records and data entry in Benchling and other platforms
  • Coordinate with external CROs and vendors on outsourced study components — review SOWs, monitor timelines, and ensure data quality

Required Qualifications

  • Bachelor's or Master's degree in Biology, Pharmacology, Biomedical Science, or related field
  • 5+ years of hands-on in vivo pharmacology experience in a biotech, pharma, or CRO environment
  • Demonstrated experience as a study director, study coordinator, or study lead — owning studies end-to-end with accountability for timelines and deliverables
  • Deep proficiency with in vivo techniques: IV, SC, IP, and PO dosing; submandibular and cardiac bleeds; necropsy; tissue collection and processing across a broad panel
  • Experience coordinating multiple concurrent studies across different programs and timelines
  • Strong organizational skills and attention to detail — you do not let things slip
  • Excellent cross-functional communication — comfortable working with scientists, RAs, vivarium staff, and leadership simultaneously
  • Self-motivated and capable of operating independently with minimal supervision
  • A genuine passion for science and for building something impactful

Preferred Qualifications

  • Experience with humanized or disease mouse models
  • Familiarity with NHP study coordination and CRO management
  • Experience with downstream bioanalytical assays — ELISA, MSD, qPCR, western blot, flow cytometry, IHC, IF
  • Familiarity with histology, tissue sectioning, and confocal imaging workflows
  • Experience with Benchling or similar LIMS platforms
  • Exposure to protein therapeutics and other modalities
  • Experience writing detailed study plans, SOPs, and IACUC protocol amendments
  • Comfortable with data analysis tools including GraphPad Prism and Microsoft Office

Pay

Base Salary Range: $106,000 - $123,000

This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.

Benefits

  • Annual performance-based target bonus
  • Stock options
  • Comprehensive medical, dental, and vision coverage
  • 401(k) plan
  • Flexible paid time off and holidays
  • Perks including on-site gym, onsite lunch, and commuter support

Contact Information

If you're excited to build a platform that combines DNA and protein multiplexing technologies, please reach out to careers@manifold.bio.

We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.

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