Associate Scientist/Senior Associate Scientist, In Vivo Pharmacology – Study Coordinator
Manifold Bio · Boston, MA · 3 wk ago
Analyst$106k–$123k/yrFull-time
Responsibilities
- Own end-to-end study coordination across multiple concurrent in vivo programs — from animal ordering and acclimation through dosing, bleeding, necropsy, tissue collection, and downstream handoff
- Develop and maintain detailed study plans, timelines, and execution schedules — including who does what, when, and how, with clear accountability at every step
- Serve as the primary point of contact between scientists, VIVO team members, vivarium staff, and external CROs — ensuring alignment on study design, timelines, and deliverables
- Contribute to study design in collaboration with program leads — including dose selection, group sizes, timepoints, route of administration, and endpoint strategy
- Perform and oversee hands-on in vivo procedures including dosing (IV, SC, IP, PO), bleeds, perfusion, necropsy, and tissue collection as needed
- Write, review, and refine study protocols and SOPs; contribute to protocol amendments as studies evolve
- Track and manage animal orders, reagent inventory, and study materials to ensure readiness ahead of each experiment
- Identify bottlenecks and resource conflicts across the study portfolio and proactively surface solutions
- Mentor and train junior VIVO team members on in vivo techniques and study execution best practices
- Maintain accurate, organized records and data entry in Benchling and other platforms
- Coordinate with external CROs and vendors on outsourced study components — review SOWs, monitor timelines, and ensure data quality
Required Qualifications
- Bachelor's or Master's degree in Biology, Pharmacology, Biomedical Science, or related field
- 5+ years of hands-on in vivo pharmacology experience in a biotech, pharma, or CRO environment
- Demonstrated experience as a study director, study coordinator, or study lead — owning studies end-to-end with accountability for timelines and deliverables
- Deep proficiency with in vivo techniques: IV, SC, IP, and PO dosing; submandibular and cardiac bleeds; necropsy; tissue collection and processing across a broad panel
- Experience coordinating multiple concurrent studies across different programs and timelines
- Strong organizational skills and attention to detail — you do not let things slip
- Excellent cross-functional communication — comfortable working with scientists, RAs, vivarium staff, and leadership simultaneously
- Self-motivated and capable of operating independently with minimal supervision
- A genuine passion for science and for building something impactful
Preferred Qualifications
- Experience with humanized or disease mouse models
- Familiarity with NHP study coordination and CRO management
- Experience with downstream bioanalytical assays — ELISA, MSD, qPCR, western blot, flow cytometry, IHC, IF
- Familiarity with histology, tissue sectioning, and confocal imaging workflows
- Experience with Benchling or similar LIMS platforms
- Exposure to protein therapeutics and other modalities
- Experience writing detailed study plans, SOPs, and IACUC protocol amendments
- Comfortable with data analysis tools including GraphPad Prism and Microsoft Office
Pay
Base Salary Range: $106,000 - $123,000
This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.
Benefits
- Annual performance-based target bonus
- Stock options
- Comprehensive medical, dental, and vision coverage
- 401(k) plan
- Flexible paid time off and holidays
- Perks including on-site gym, onsite lunch, and commuter support
Contact Information
If you're excited to build a platform that combines DNA and protein multiplexing technologies, please reach out to careers@manifold.bio.
We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.